Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
LC3 and p62/SQSTM1 (zeige SQSTM1 ELISA Kits) have roles in early-stage non-small cell lung cancer
Hotspot mutations in the arginine-rich stretch in MAP1LC3A resulting in reduced cleavage of MAP1LC3A by ATG4B (zeige ATG4B ELISA Kits) both in vitro and in vivo, suggesting a functional implication of this gene mutation in cancer development.
FYCO1 (zeige FYCO1 ELISA Kits) and MAP1LC3A interact through a novel binding mode that involves Atg8 (zeige GABARAPL2 ELISA Kits)-family proteins
analysis of soluble SQSTM1 (zeige SQSTM1 ELISA Kits) complexes and soluble complexes formed between SQSTM1 (zeige SQSTM1 ELISA Kits) oligomers and LC3 using a combination of fluorescence microscopy-based biophysical approaches in living cells
we found that ATG14 interacted with Ulk1 and LC3, and knock down of Ulk1 prevented the lipidation of LC3 and autophagy in HeLa-ATG14 cells. We also identified a phosphatidylethanolamine (PE) binding region in ATG14, and the addition of Ulk1 to Hela-ATG14 cells decreased the ATG14-PE interaction.
Legionella pneumophila RavZ extracts LC3-PE from the membrane before deconjugation. RavZ initially recognizes the LC3 molecule on membranes via its N-terminal LC3-interacting region (LIR (zeige CD300C ELISA Kits)) motif.
The results are consistent with a model in which RPIA (zeige RPIA ELISA Kits) suppresses autophagy and LC3 processing by modulation of redox signaling.
can act as a negative mediator in autophagy through stimulation of the AKT (zeige AKT1 ELISA Kits)-MTORC1 pathway and direct interaction with LC3.
Data show that p62 interaction with LC3, leading to the delivery of p62 and its cargoes to the autophagosome.
LC3 puncta were still present in the granular layer of nonlesional psoriatic epidermis but at a much lower level compared with healthy adult epidermis, whereas in lesional psoriatic skin, LC3 was not expressed at all.
paxillin (zeige PXN ELISA Kits) interacts with processed LC3 through a conserved LIR (zeige CD300C ELISA Kits) motif in the amino-terminal end of paxillin (zeige PXN ELISA Kits) and that this interaction is regulated by oncogenic SRC (zeige SRC ELISA Kits) activity.
These results suggest that the Golgi complex may serve as a membrane platform for noncanonical autophagy where V-ATPase (zeige ATP6V1H ELISA Kits) is (zeige ATP11A ELISA Kits) a key player.
LC3 was down regulated in the hypothalamus of diabetic mice.
LC3 overexpression in 3T3-L1 preadipocytes stimulates adipocyte differentiation via direct modulation of RKIP (zeige PEBP1 ELISA Kits)-dependent ERK1 (zeige MAPK3 ELISA Kits) activity.
Development of LC3/GABARAP (zeige GABARAP ELISA Kits) sensors containing a LIR (zeige CD300C ELISA Kits) and a hydrophobic domain to monitor autophagy.
These findings demonstrate that LC3 contributes to melanogenesis by increasing ERK (zeige EPHB2 ELISA Kits)-dependent MITF (zeige MITF ELISA Kits) expression, thereby providing a mechanistic insight into the signaling network that links autophagy to melanogenesis.
LC3 is exploited by coxsackievirus in both autophagy-dependent and -independent manners in vivo
LC3 overexpression thus exerts neuroprotection through increasing alpha7nAChR expression for eAbeta binding and further enhancing autophagic activity for Abeta (zeige APP ELISA Kits) clearance in vitro and in vivo.
we describe basic protocols to measure the levels of endogenous LC3 and p62 by immunoblotting in cultured mammalian cells
Hedgehog (zeige SHH ELISA Kits) signaling is required for the Lc3 synthase (zeige B3GNT5 ELISA Kits) expression in embryonic lens
LC3 is localized in porcine oocytes during in vitro maturation.
Data suggest that expression of MAP1LC3A in graafian follicle/granulosa cell/theca cell is distinct in normal pigs versus miniature pigs; expression of MAP1LC3A is higher in normal pigs than in miniature pigs; MAP1LC3A may be marker of autophagy.
Data indicate that the expression of MAP1LC3A, B and autophagy-associated genes (ATG5 (zeige ATG5 ELISA Kits), mTOR (zeige FRAP1 ELISA Kits), Beclin-1 (zeige BECN1 ELISA Kits)) was increased in normal pigs, while decreased in miniature pigs.
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
microtubule-associated protein 1 light chain 3 alpha
, 35-alpha calcimedin
, Annexin III (Lipocortin III)
, lipocortin III
, placental anticoagulant protein III
, MAP1 light chain 3-like protein 1
, MAP1A/1B light chain 3 A
, MAP1A/MAP1B LC3 A
, MAP1A/MAP1B light chain 3 A
, autophagy-related ubiquitin-like modifier LC3 A
, microtubule-associated proteins 1A/1B light chain 3
, microtubule-associated proteins 1A/1B light chain 3A
, autophagy-related protein LC3 A
, microtubule-associated protein 1-light chain 3A
, microtubule-associated proteins 1A/1B light chain 3B
, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5A
, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
, beta-1,3-N-acetylglucosaminyltransferase 5A
, lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A
, lactotriaosylceramide synthase A
, lc(3)Cer synthase A
, lc3 synthase A