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Human GABARAPL1 Protein expressed in Escherichia coli (E. coli) - ABIN2006228
Choi, Lee, Lee, Kim: Rapid detection of 6×-histidine-labeled recombinant proteins by immunochromatography using dye-labeled cellulose nanobeads. in Biotechnology letters 2015
Our data demonstrated that a specific decrease of GABARAPL1 expression in breast cancers was associated with both DNA methylation (zeige HELLS Proteine) and histone deacetylation and that CREB-1 (zeige CREB1 Proteine) recruitment on GABARAPL1
Androgen deprivation downregulates Gabarapl1 in an AR dependent manner, resulting in the increase of autophagy flux
Results showed that the mRNA and protein levels of GABARAPL1 and GATE-16 (zeige GABARAPL2 Proteine) were decreased in the cerebellum of multiple system atrophy relative to controls
GABARAPL1 plays an important role in cell proliferation, invasion, and autophagic flux, as well as in mitochondrial homeostasis and cellular metabolic programs in a breast cancer cell line.
Kaplan-Meier survival analysis showed a significant association between low GABARAPL1 expression and poor prognosis of HCC (zeige FAM126A Proteine) patients.
Lipidation of the LC3 (zeige MAP1LC3A Proteine)/GABARAP (zeige GABARAP Proteine) family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3 (zeige ATG3 Proteine).
Data demonstrate that HSP90 (zeige HSP90 Proteine) interacts and protects GABARAPL1 from its degradation by the proteasome.
analysis of specific functions of GABARAPL1 [review]
Atg8 (zeige GABARAPL2 Proteine) interacting motif (AIM) in Stbd1 (zeige STBD1 Proteine) is necessary for GABARAPL1 binding.
Results indicate that the presence of a tryptophan residue in the LIR (zeige CD300C Proteine) motif increases the binding affinity of GABARAPL-1/NBR1 (zeige NBR1 Proteine)-LIR (zeige CD300C Proteine) complex.
Cells that lacked GABARAPs and mice that lacked Gate-16 (zeige GABARAPL2 Proteine) alone were defective in the IFN-gamma-induced (zeige SAMHD1 Proteine) clearance of vacuolar pathogens such as Toxoplasma. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of interferon (zeige IFNA Proteine)-inducible GTPases.
study of cerebral GABARAPL1 protein expression provides insight into its role in the development and homeostasis of the mouse brain
GABARAPL1 negatively regulates Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) signaling by mediating Dvl2 (zeige DVL2 Proteine) degradation through the autophagy pathway.
because of its stronger binding for hKOPR, GEC1 is able to be recruited by hKOPR sufficiently without membrane association via its C-terminal modification; however, du GABARAP (zeige GABARAP Proteine) appears to require C-terminal modifications to enhance KOPR expression.
Expression of mouse Atg8L in HEK293 cells led to cleavage of its C-terminus. (Atg8L/Apg8l)and is the fourth modifier of mammalian Atg8 (zeige MAP1LC3B Proteine) conjugation. (ATG8L/Apg8L)
Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor (By similarity).
GABA(A) receptor-associated protein like 1
, gamma-aminobutyric acid receptor-associated protein-like 1
, GABA(A) receptor-associated protein-like 1
, GABA(A) receptors associated protein like 3
, early estrogen-regulated protein
, glandular epithelial cell protein 1
, MDBK gamma-aminobutyric acid-receptor-associated protein
, gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1