anti-Maus TREX1 Antikörper für Immunofluorescence

Recommended TREX1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
three Prime Repair Exonuclease 1 (TREX1) Antikörper
  • AGS1
  • CRV
  • DRN3
  • HERNS
  • 1661
  • AU041952
  • RGD1309596
  • three prime repair exonuclease 1
  • CpipJ_CPIJ012074
  • Tsp_03749
  • TREX1
  • Trex1
Epitop
AA 82-179
5
4
4
4
3
3
3
3
2
2
2
1
1
1
1
Reaktivität
Maus
57
11
9
Wirt
Maus
30
29
Klonalität
Monoklonal
Konjugat
Dieser TREX1 Antikörper ist unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
53
37
25
16
12
5
5
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN968709
146,73 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN968710 IF WB Mouse IgG1 AA 82-179 Anmelden zum Anzeigen 29-TREX1 2
1 ABIN4362286 ELISA ICC IF IHC IHC (p) WB Rabbit Center Anmelden zum Anzeigen Polyclonal
1 ABIN2751825 ELISA IF IHC IP WB FITC Rabbit IgG AA 220-245 Anmelden zum Anzeigen Polyclonal
1 ABIN2751824 ELISA IF IHC IP WB Rabbit IgG AA 220-245 Anmelden zum Anzeigen Polyclonal
1 ABIN5558687 ELISA IF IHC IP WB Biotin Rabbit Anmelden zum Anzeigen Polyclonal

anti-TREX1 Antikörper für Immunofluorescence mit den meisten Publikationen

Ähnliche anti-TREX1 Antikörper

Applikation / Reaktivität Maus
ELISA 8 Antikörper
Enzyme Immunoassay (EIA) 1 Antikörper
Immunocytochemistry (ICC) 1 Antikörper
Immunofluorescence (IF) 6 Antikörper
Immunohistochemistry (IHC) 8 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antikörper
Immunoprecipitation (IP) 3 Antikörper
Western Blotting (WB) 12 Antikörper

General

Antigen three Prime Repair Exonuclease 1 (TREX1) Antikörper
Epitop AA 82-179
(5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Maus
(57), (11), (9)
Wirt Maus
(30), (29)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser TREX1 Antikörper ist unkonjugiert
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (IF), Western Blotting (WB)
(53), (37), (25), (16), (12), (5), (5), (2), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TREX1 Antikörper

Target Details TREX1 Anwendungsinformationen Handhabung ProductDetails: References for anti-TREX1 antibody (ABIN968709) Bilder
Produktmerkmale 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Mouse TREX1 aa. 82-179
Klon 29-TREX1
Isotyp IgG1

Target Details TREX1

Produktdetails anti-TREX1 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-TREX1 antibody (ABIN968709) Bilder zurück nach oben
Antigen
Andere Bezeichnung TREX1 (TREX1 Antibody Abstract)
Hintergrund DNA replication, repair, and recombination requires the excision of nucleotides from the DNA 3' termini. Many 3' to 5' exonucleases have been identified which catalyze the excision of monophosphates from the 3' termini of DNA. TREX1 and TREX2 are 3' to 5' exonucleases that contain three conserved exonuclease active site motifs (EASM) that may produce exonuclease activity. TREX1 and TREX2 are most closely related to the proofreading exonucleases of the bacterial replicative DNA polymerases and the RNase T enzymes. Recombinant expression of TREX1 and TREX2 demonstrates that they have exonuclease activity when oligonucleotide is present. TREX1 shows the greatest exonuclease activity with partial duplex DNA, and no activity with single-stranded RNA or an RNA-DNA partial duplex. In addition, reconstitution of TREX1 with DNA polymerase beta and DNA ligase III-XRCC1 facilitates accurate rejoining of a 3' mismatched base residue at a single-strand break. Thus, TREX1 and TREX2 are 3' to 5' exonucleases that may be important for excision of nucleotides during DNA replication, repair, and recombination.
Molekulargewicht 32 kDa
Forschungsgebiet Immunology, DNA/RNA
Pathways Apoptose

Anwendungsinformationen

Produktdetails anti-TREX1 Antikörper Target Details TREX1 Handhabung ProductDetails: References for anti-TREX1 antibody (ABIN968709) Bilder zurück nach oben
Kommentare

Related Products: ABIN967389

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TREX1 Antikörper Target Details TREX1 Anwendungsinformationen ProductDetails: References for anti-TREX1 antibody (ABIN968709) Bilder zurück nach oben
Format Liquid
Konzentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store undiluted at -20°C.

ProductDetails: References for anti-TREX1 antibody (ABIN968709)

Produktdetails anti-TREX1 Antikörper Target Details TREX1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Höss, Robins, Naven, Pappin, Sgouros, Lindahl: "A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein." in: The EMBO journal, Vol. 18, Issue 13, pp. 3868-75, 1999

Mazur, Perrino: "Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases." in: The Journal of biological chemistry, Vol. 274, Issue 28, pp. 19655-60, 1999

Bilder

Produktdetails anti-TREX1 Antikörper Target Details TREX1 Anwendungsinformationen Handhabung ProductDetails: References for anti-TREX1 antibody (ABIN968709) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-TREX1 Antikörper (three Prime Repair Exonuclease 1) (AA 82-179) (ABIN968709) Western blot analysis of TREX1 on a BC3H1 cell lysate (Mouse brain smooth muscle-like...