anti-Schwein TNFSF10 Antikörper für Western Blotting

Recommended TNFSF10 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Antikörper
  • TRAIL
  • tl2
  • apo2l
  • cd253
  • trail
  • apo-2l
  • trail1
  • xtrail1
  • APO2L
  • Apo-2L
  • CD253
  • TL2
  • A330042I21Rik
  • AI448571
  • APO-2L
  • Ly81
  • Trail
  • tumor necrosis factor (ligand) superfamily, member 10
  • TNF-related apoptosis inducing ligand-like
  • TNFSF10
  • TRAIL-LIKE
  • tnfsf10
  • Tnfsf10
Epitop
N-Term
44
26
15
11
6
6
5
5
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Hund, Human, Schwein
335
79
37
3
2
2
1
1
1
Wirt
Kaninchen
206
159
24
2
1
Klonalität
Polyklonal
Konjugat
Dieser TNFSF10 Antikörper ist unkonjugiert
40
22
16
10
6
6
4
4
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
255
128
118
63
54
28
19
17
15
13
11
10
9
5
3
2
2
2
2
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2792132
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.0963302 ABIN926879 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN216393 WB Rabbit IgG AA 56-105 Anmelden zum Anzeigen Polyclonal

General

Antigen Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Antikörper
Epitop N-Term
(44), (26), (15), (11), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Hund, Human, Schwein
(335), (79), (37), (3), (2), (2), (1), (1), (1)
Wirt Kaninchen
(206), (159), (24), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser TNFSF10 Antikörper ist unkonjugiert
(40), (22), (16), (10), (6), (6), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(255), (128), (118), (63), (54), (28), (19), (17), (15), (13), (11), (10), (9), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TNFSF10 Antikörper

Target Details TNFSF10 Anwendungsinformationen Handhabung Referenzen für anti-TNFSF10 Antikörper (ABIN2792132) Bilder
Sequenz CFLKEDDSYW DPNDEESMNS PCWQVKWQLR QLVRKMILRT SEETISTVQE
Homologie Dog: 80%, Human: 100%, Pig: 78%
Produktmerkmale This is a rabbit polyclonal antibody against TNFSF10. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TNFSF10

Target Details TNFSF10

Produktdetails anti-TNFSF10 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TNFSF10 Antikörper (ABIN2792132) Bilder zurück nach oben
Antigen
Andere Bezeichnung TNFSF10 (TNFSF10 Antibody Abstract)
Hintergrund TNFSF10 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3.
Alias Symbols: TL2, APO2L, CD253, TRAIL, Apo-2L
Protein Interaction Partner: CASP8, CASP3, CFLAR, TNFRSF10B, FADD, RIPK1, TRAF2, TNFAIP3, SOCS3, RBM48, TNFRSF10D, TNFRSF10C, TNFRSF10A, TNFSF10, TNFRSF11B, ACP5, IER3, CREBBP, SP3, SP1, HDAC5, HDAC4, HDAC3, HDAC2, HDAC1, HIST3H3,
Protein Size: 281
Molekulargewicht 33 kDa
Gen-ID 8743
NCBI Accession NM_003810, NP_003801
UniProt P50591
Pathways Apoptose, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails anti-TNFSF10 Antikörper Target Details TNFSF10 Handhabung Referenzen für anti-TNFSF10 Antikörper (ABIN2792132) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Kommentare

Antigen size: 281 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TNFSF10 Antikörper Target Details TNFSF10 Anwendungsinformationen Referenzen für anti-TNFSF10 Antikörper (ABIN2792132) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TNFSF10 Antikörper (ABIN2792132)

Produktdetails anti-TNFSF10 Antikörper Target Details TNFSF10 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Ceballos, Parody, Quiroga, Casella, Francés, Larocca, Carnovale, Alvarez, Carrillo: "FoxO3a nuclear localization and its association with β-catenin and Smads in IFN-α-treated hepatocellular carcinoma cell lines." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 34, Issue 11, pp. 858-69, 2014

Allgemeine Veröffentlichungen

Wu, Tsai, Lin, Chou, Chen, Yang, Hsu, Hsu: "Helicobacter pylori enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in human gastric epithelial cells." in: World journal of gastroenterology : WJG, Vol. 10, Issue 16, pp. 2334-9, 2004

Bilder

Produktdetails anti-TNFSF10 Antikörper Target Details TNFSF10 Anwendungsinformationen Handhabung Referenzen für anti-TNFSF10 Antikörper (ABIN2792132) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (N-Term) antibody (ABIN2792132) WB Suggested Anti-TNFSF10 Antibody Titration: 0.2-1 ug/ml
Positive Contr...