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Navigieren Sie durch unsere anti-PARP1 (PARP1) Antikörper

Full name:
anti-Poly (ADP-Ribose) Polymerase 1 Antikörper (PARP1)
Auf www.antikoerper-online.de finden Sie aktuell 423 Poly (ADP-Ribose) Polymerase 1 (PARP1) Antikörper von 27 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PARP1 Kits (26) und PARP1 Proteine (26) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 503 PARP1 Produkte verfügbar.
Synonyme:
5830444G22Rik, Adprp, Adprt, ADPRT 1, Adprt1, AI893648, ARTD1, BEST:LD21673, C80510, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, dPARP, LD21673.3prime, padprt-1, parp, parp-1, PARP1, ppol, sPARP-1
Alle Antikörper anzeigen Gen GeneID UniProt
PARP1 142 P09874
PARP1 25591 P27008
PARP1 11545  

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Meistgesuchte Reaktivitäten zu anti-PARP1 (PARP1) Antikörper

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anti-Human PARP1 Antikörper:

anti-Rat (Rattus) PARP1 Antikörper:

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Am meisten referenzierte anti-PARP1 Antikörper

  1. Human Polyclonal PARP1 Primary Antibody für IP, IHC - ABIN2854261 : Lamarre, Talbot, de Murcia, Laplante, Leduc, Mazen, Poirier: Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study. in Biochimica et biophysica acta 1988 (PubMed)
    Zeige alle 8 Referenzen für ABIN2854261

  2. Human Monoclonal PARP1 Primary Antibody für IF, WB - ABIN394297 : Lee, Bang, Park, Kim, Shin, Bae: Lack of association between poly(ADP-ribose) polymerase (PARP) polymorphisms and rheumatoid arthritis in a Korean population. in Rheumatology international 2012 (PubMed)
    Zeige alle 5 Referenzen für ABIN394297

  3. Human Polyclonal PARP1 Primary Antibody für WB - ABIN1881627 : Dong, Bey, Li, Kabbani, Yan, Xie, Hsieh, Gao, Boothman: Prostate cancer radiosensitization through poly(ADP-Ribose) polymerase-1 hyperactivation. in Cancer research 2010 (PubMed)
    Zeige alle 4 Referenzen für ABIN1881627

  4. Human Polyclonal PARP1 Primary Antibody für WB - ABIN1881628 : Krishnakumar, Kraus: PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway. in Molecular cell 2010 (PubMed)
    Zeige alle 4 Referenzen für ABIN1881628

  5. Human Polyclonal PARP1 Primary Antibody für ChIP, WB - ABIN2668274 : Kim, Mauro, Gévry, Lis, Kraus: NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. in Cell 2004 (PubMed)
    Zeige alle 2 Referenzen für ABIN2668274

  6. Human Polyclonal PARP1 Primary Antibody für EIA, WB - ABIN358977 : Tao, Gao, Hoffman, Liu: Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif. in Biochemistry 2008 (PubMed)
    Zeige alle 2 Referenzen für ABIN358977

  7. Human Polyclonal PARP1 Primary Antibody für ChIP, WB - ABIN2668275 : Ratnakumar, Duarte, LeRoy, Hasson, Smeets, Vardabasso, Bönisch, Zeng, Xiang, Zhang, Li, Wang, Hake, Schermelleh, Garcia, Bernstein: ATRX-mediated chromatin association of histone variant macroH2A1 regulates ?-globin expression. in Genes & development 2012 (PubMed)

  8. Chicken Polyclonal PARP1 Primary Antibody für WB - ABIN2778108 : Pétrilli, Herceg, Hassa, Patel, Di Paola, Cortes, Dugo, Filipe, Thiemermann, Hottiger, Cuzzocrea, Wang: Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. in The Journal of clinical investigation 2004 (PubMed)

  9. Human Polyclonal PARP1 Primary Antibody für IF (p), IHC (p) - ABIN677903 : Ma, Liu, Wang, Liu, Chen, Valle, Zuo, Xia, Liu: Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals. in ACS nano 2015 (PubMed)

Weitere Antikörper gegen PARP1 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Poly (ADP-Ribose) Polymerase 1 (PARP1) Interaktionspartner

  1. A mutation of Parp also increases NAD+ levels; although, this was only observed in parkin (zeige PARK2 Antikörper) mutant flies and not in the heterozygous Parp mutants, possibly owing to an increased PARP activity in the parkin (zeige PARK2 Antikörper) mutants.

  2. chromatin loosening and associated initiation of gene expression is activated by phosphorylation of H2Av (zeige H2AFV Antikörper) in a nucleosome positioned in promoter regions of PARP-1-dependent genes

  3. Based on these findings, we propose a model that explains how PARP1 activity impacts nucleolar functions and, consequently, ribosomal biogenesis

  4. PARP is associated with the 5' end of Hsp70, and its enzymatic activity is rapidly induced by heat shock leading to nucleosome loss.

  5. Activation of PARP-1 overexpression in the imago results in extension of the lifespan in females and males. The lifespan increase in females with PARP-1 conditional overexpression was accompanied by decrease of fertility.

  6. PARP1 is targeted to chromatin by association with the histone H2A variant (H2Av).

  7. demonstrate that this alteration specifically excludes PARP1 protein from heterochromatin and makes PARP1 unable to maintain repression of retrotransposable elements.

  8. PARP-e autoregulates Parp transcription

  9. propose that chromosomal PARP molecules become activated by developmental or environmental cues and strip nearby chromatin proteins off DNA to generate a puff

  10. PARP1 is required for protein targeting to Cajal body.

Human Poly (ADP-Ribose) Polymerase 1 (PARP1) Interaktionspartner

  1. Curcumin induces apoptosis in leukemia cells via PARP-1 mediated caspase-3 (zeige CASP3 Antikörper) dependent pathway.

  2. the effect of PARP1 Val762Ala polymorphism in treatment response in cervical cancer patients

  3. Overexpression of miR (zeige MLXIP Antikörper)-335 decreased the expression of PARP-1 mRNA and protein, and NF-kappaB (zeige NFKB1 Antikörper) protein levels were correspondingly downregulated, thus regulating the chemo-radiosensitivity of small cell lung cancer cells.

  4. Participants were genotyped for a functional non-synonymous single-nucleotide polymorphism (2456T/C; rs1136410) that results in the conversion of a conserved valine residue to alanine (762Val/Ala) in the amino-acid sequence of PARP-1

  5. This review assesses current developments in PARP-1 biology and activation signals for PARP-1, other than conventional DNA damage activation. [review]

  6. High expression of PARP1 is significantly associated with chordoma invasion and recurrence. PARP1 may become a potential biomarker for chordoma in predicting its recurrence and patients' prognosis.

  7. During live-cell imaging, 53BP1 (zeige TP53BP1 Antikörper)-GFP focus formation was observed within 10 minutes after UVC irradiation. Most 53BP1 (zeige TP53BP1 Antikörper) foci resolved by 100 minutes. To block UVC-induced double-strand break repair in cancer cells, poly(ADP-ribose) polymerase (PARP) was targeted with ABT-888 (veliparib). PARP (zeige COL11A2 Antikörper) inhibition markedly enhanced UVC-irradiation-induced persistence of 53BP1 (zeige TP53BP1 Antikörper)-foci

  8. In a population of Sicilian patients with Parkinson's disease, the PARP-1 - 410 C/T genotype was not associated with protection from Parkinson's disease.

  9. Collectively, our results suggest that PARP1 imaging with PARPi-FL can enhance the detection of oral cancer, serve as a screening tool and help to guide surgical resections.

  10. This meta-analysis suggests that PARP1 rs1136410 T>C may play a significant role in the protection against the development of brain tumors and glioma.

Cow (Bovine) Poly (ADP-Ribose) Polymerase 1 (PARP1) Interaktionspartner

  1. no difference was found in the level of SBDP145 between muscles, while SBDP120 and PARP-1 cleavage products were not detected

  2. ADPRT Val762Ala and APE1 (zeige APEX1 Antikörper) Asp148Glu polymorphisms are not associated with increased breast cancer risk

  3. analysis of poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites

  4. FGF2 (zeige FGF2 Antikörper) stimulates poly(ADP-ribose) polymerase activity by a DNA strand breaks-independent manner which involves a mitogen-activated protein kinases (MAPK (zeige MAPK1 Antikörper))-dependent pathway

Mouse (Murine) Poly (ADP-Ribose) Polymerase 1 (PARP1) Interaktionspartner

  1. ARTD1 controls osteoclast development and bone remodelling via its enzymatic activity by modulating the epigenetic marks surrounding the IL-1beta (zeige IL1B Antikörper) promoter and expression of IL-1beta (zeige IL1B Antikörper) and subsequently also Nfatc1 (zeige NFATC1 Antikörper)/A.

  2. the role of PARP-1 in age-dependent changes in endothelial cell function and its underlying mechanism

  3. Both depletion of PARP-1 and inhibition of PARP-1 activity augmented LXR (zeige NR1H3 Antikörper) ligand-induced ABCA1 (zeige ABCA1 Antikörper) expression in the RAW 264.7 macrophage line and primary bone marrow-derived macrophages but did not affect LXR (zeige NR1H3 Antikörper)-dependent expression of other target genes, ABCG1 (zeige ABCG1 Antikörper) and SREBP-1c (zeige SREBF1 Antikörper).

  4. unless it is degraded, ARTD1 represses OC development through transcriptional regulation.

  5. The protective effects conferred by Parp1 deletion were lost in Rag2 (zeige RAG2 Antikörper)(-/-) x Parp1(-/-) mice, highlighting the role of the adaptive immune system for full protection.

  6. Data show reduced tumor burden through increased oxidative stress in lung adenocarcinoma cells of PARP-1 and PARP-2 (zeige PARP2 Antikörper) knockout mice.

  7. By enhancing PARP1 activity, ULK1 (zeige ULK1 Antikörper) contributes to ATP depletion and death of H2O2-treated cells.

  8. PARP-1 deficiency significantly increased the chromatin binding affinity of MeCP2 (zeige MECP2 Antikörper) in vivo.

  9. these results identify CHD1L (zeige CHD1L Antikörper) as a key chromatin remodeler involved in PARP1/PARylation-regulated early-stage reprogramming and pluripotency in stem cells.

  10. PARP-1 activation is required for the consolidation, reconsolidation, and extinction of contextual fear memory

PARP1 Antigen-Profil

Beschreibung des Gens

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Alternative names and synonyms associated with PARP1

  • Poly-(ADP-ribose) polymerase (Parp) Antikörper
  • poly (ADP-ribose) polymerase 1 (PARP1) Antikörper
  • poly (ADP-ribose) polymerase 1 (Parp1) Antikörper
  • poly (ADP-ribose) polymerase 1 (parp1) Antikörper
  • poly (ADP-ribose) polymerase family, member 1 (Parp1) Antikörper
  • poly ADP-ribose polymerase (Parp) Antikörper
  • 5830444G22Rik Antikörper
  • Adprp Antikörper
  • Adprt Antikörper
  • ADPRT 1 Antikörper
  • Adprt1 Antikörper
  • AI893648 Antikörper
  • ARTD1 Antikörper
  • BEST:LD21673 Antikörper
  • C80510 Antikörper
  • CG17685 Antikörper
  • CG17696 Antikörper
  • CG17718 Antikörper
  • CG40411 Antikörper
  • D.PARP Antikörper
  • Dm.pARTa Antikörper
  • Dmel\\CG40411 Antikörper
  • dPARP Antikörper
  • LD21673.3prime Antikörper
  • padprt-1 Antikörper
  • parp Antikörper
  • parp-1 Antikörper
  • PARP1 Antikörper
  • ppol Antikörper
  • sPARP-1 Antikörper

Bezeichner auf Proteinebene für PARP1

CG40411-PB , CG40411-PC , Parp-PB , Parp-PC , Poly(ADP ribose) polymerase 1 , Poly(ADP)-Ribose polymerase , Poly(ADP-)Ribose polymerase , Poly(ADP-ribose) polymerase , Poly(ADP-ribose) polymerase 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) , ADP-ribosyltransferase NAD(+) , ADP-ribosyltransferase diphtheria toxin-like 1 , NAD(+) ADP-ribosyltransferase 1 , poly (ADP-ribose) polymerase family, member 1 , poly [ADP-ribose] polymerase 1 , poly(ADP-ribose) polymerase , poly(ADP-ribose) synthetase , poly(ADP-ribosyl)transferase , poly[ADP-ribose] synthase 1 , ADP-ribosyltransferase (NAD+ , ADP-ribosyltransferase 1 , ADPRT 1 , poly (ADP-ribose) polymerase) , poly(ADP-ribose) polymerase PARP-1 , poly[ADP-ribose] synthetase 1 , ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase) , PARP-1 , ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1 , msPARP , Poly[ADP-ribose] synthase 1

GENE ID SPEZIES
3355109 Drosophila melanogaster
142 Homo sapiens
25591 Rattus norvegicus
286764 Bos taurus
397928 Xenopus laevis
396199 Gallus gallus
490385 Canis lupus familiaris
11545 Mus musculus
100689463 Cricetulus griseus
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