anti-Ratte (Rattus) FASL Antikörper für Immunofluorescence

Recommended FASL Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Fas Ligand (TNF Superfamily, Member 6) (FASL) Antikörper
  • fasl
  • FASL
  • FASLG
  • FAS
  • TNFRSF6
  • zgc:162027
  • TNFSF6
  • ALPS1B
  • APT1LG1
  • APTL
  • CD178
  • CD95-L
  • CD95L
  • Fas-L
  • Faslg
  • Tnfsf6
  • gld
  • Apt1Lg1
  • Fasl
  • Fas ligand L homeolog
  • Fas cell surface death receptor
  • Fas ligand
  • Fas ligand (TNF superfamily, member 6)
  • faslg.L
  • FAS
  • FASLG
  • faslg
  • fas
  • Fasl
  • Faslg
Reaktivität
Maus, Ratte (Rattus)
421
173
88
36
7
5
5
3
3
2
1
1
Wirt
Hamster
259
176
48
32
29
7
1
Klonalität
Monoklonal
Konjugat
Dieser FASL Antikörper ist unkonjugiert
45
31
27
12
12
9
9
9
9
8
8
8
8
8
7
6
6
4
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
313
257
124
95
80
75
51
46
28
28
13
11
10
10
7
5
3
2
2
1
1
1
1
1
1
1
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Bilder

Produktnummer ABIN2665564
Preis und Verfügbarkeit auf Anfrage.

General

Antigen Fas Ligand (TNF Superfamily, Member 6) (FASL) Antikörper
Reaktivität Maus, Ratte (Rattus)
(421), (173), (88), (36), (7), (5), (5), (3), (3), (2), (1), (1)
Wirt Hamster
(259), (176), (48), (32), (29), (7), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser FASL Antikörper ist unkonjugiert
(45), (31), (27), (12), (12), (9), (9), (9), (9), (8), (8), (8), (8), (8), (7), (6), (6), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
(313), (257), (124), (95), (80), (75), (51), (46), (28), (28), (13), (11), (10), (10), (7), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FASL Antikörper

Target Details FASL Anwendungsinformationen Handhabung Referenzen für anti-FASL Antikörper (ABIN2665564) Bilder
Marke LEAF™
Reinigung The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterilität 0.2 μm filtered
Endotoxin-Niveau

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Klon MFL4
Isotyp IgG

Target Details FASL

Produktdetails anti-FASL Antikörper Anwendungsinformationen Handhabung Referenzen für anti-FASL Antikörper (ABIN2665564) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD178 (FASL Antibody Abstract)
Hintergrund CD178 is a 40 kD member of the TNF/NGF superfamily also known as Fas ligand, FasL, Apo-1 ligand, and CD95 ligand. Cell surface CD178 is expressed on activated T cells and in testis and eye. CD178 is upregulated in activated T cells upon TCR re-engagement and has been shown to induce autocrine and paracrine T cell death. CD178 expression in the eye and testis has been shown to participate in immune privilege at these sites. CD178 can be cleaved from the surface by metalloproteases, and "soluble" CD178 may block the activities of membrane-bound CD178. CD178 binds to CD95 (Fas) to induce apoptotic cell death implicated in the maintenance of peripheral tolerance. CD178/CD95 interactions have also been implicated in the proliferation of CD8+ cells and neutrophil extravasation, chemotaxis, and survival. The MFL4 antibody recognizes CD178 in a wide array of mouse strains and has been reported to block CD178/CD95 induced apoptosis. The MFL4 antibody is cross-reactive with rat and mouse FasL.
Pathways Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails anti-FASL Antikörper Target Details FASL Handhabung Referenzen für anti-FASL Antikörper (ABIN2665564) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FASL Antikörper Target Details FASL Anwendungsinformationen Referenzen für anti-FASL Antikörper (ABIN2665564) Bilder zurück nach oben
Konzentration 1.0 mg/mL
Konservierungsmittel Azide free
Handhabung This LEAF™ solution contains no preservative, handle under aseptic conditions
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-FASL Antikörper (ABIN2665564)

Produktdetails anti-FASL Antikörper Target Details FASL Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Chang, Chang, Lee, Chiang, Chuang, Kuo, Yang: "Cytopiloyne, a polyacetylenic glucoside, prevents type 1 diabetes in nonobese diabetic mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 11, pp. 6984-93, 2007

Borges, Falcão, Leite-Júnior, Alvim, Teixeira, Russo, Nóbrega, Lopes, Rocco, Davidson, Linden, Yagita, Zin, DosReis: "Fas ligand triggers pulmonary silicosis." in: The Journal of experimental medicine, Vol. 194, Issue 2, pp. 155-64, 2001

Trinité, Voisine, Yagita, Josien: "A subset of cytolytic dendritic cells in rat." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 8, pp. 4202-8, 2000

Hill, Ouhtit, Loughlin, Kripke, Ananthaswamy, Owen-Schaub: "Fas ligand: a sensor for DNA damage critical in skin cancer etiology." in: Science (New York, N.Y.), Vol. 285, Issue 5429, pp. 898-900, 1999

Kayagaki, Yamaguchi, Nagao, Matsuo, Maeda, Okumura, Yagita: "Polymorphism of murine Fas ligand that affects the biological activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3914-9, 1997

Takahashi, Tanaka, Brannan, Jenkins, Copeland, Suda, Nagata: "Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand." in: Cell, Vol. 76, Issue 6, pp. 969-76, 1994

Bilder

Produktdetails anti-FASL Antikörper Target Details FASL Anwendungsinformationen Handhabung Referenzen für anti-FASL Antikörper (ABIN2665564) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) antibody (ABIN2665564) anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) antibody