anti-Human FASL Antikörper für Mass Cytometry

Recommended FASL Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Fas Ligand (TNF Superfamily, Member 6) (FASL) Antikörper
  • fasl
  • FASL
  • FASLG
  • FAS
  • TNFRSF6
  • zgc:162027
  • TNFSF6
  • ALPS1B
  • APT1LG1
  • APTL
  • CD178
  • CD95-L
  • CD95L
  • Fas-L
  • Faslg
  • Tnfsf6
  • gld
  • Apt1Lg1
  • Fasl
  • Fas ligand (TNF superfamily, member 6)
  • Fas (TNF receptor superfamily, member 6)
  • fas ligand
  • faslg
  • FAS
  • FASLG
  • fas
  • LOC100344073
  • Fasl
  • Faslg
Reaktivität
Human
403
174
89
36
7
5
5
3
3
2
1
1
Wirt
Maus
241
175
49
32
29
8
1
Klonalität
Monoklonal
Konjugat
Dieser FASL Antikörper ist konjugiert mit PE
44
29
26
11
11
8
8
8
8
7
7
7
7
7
6
5
5
4
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Mass Cytometry (CyTOF)
298
244
111
97
80
75
38
34
28
28
13
12
10
10
5
4
3
2
2
2
1
1
1
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2663099
258,82 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2663100 FACS CyTOF PE Mouse IgG1 kappa Anmelden zum Anzeigen NOK-1 8

anti-FASL Antikörper für Mass Cytometry mit den meisten Publikationen

Ähnliche anti-FASL Antikörper

Applikation / Reaktivität Human
Blocking Antibody (Inhibition) 2 Antikörper
Cell-ELISA (cELISA) 1 Antikörper
Cellular Assay (CA) 1 Antikörper
Cytometry by Time of Flight (CyTOF) 4 Antikörper
Dot Blot (DB) 1 Antikörper
ELISA 98 Antikörper
ELISA (Capture) 1 Antikörper
ELISpot 1 Antikörper
Enzyme Immunoassay (EIA) 10 Antikörper
Flow Cytometry (FACS) 199 Antikörper
Functional Studies (Func) 20 Antikörper
Immunoassay (IA) 1 Antikörper
Immunochromatography (IC) 2 Antikörper
Immunocytochemistry (ICC) 31 Antikörper
Immunofluorescence (IF) 32 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 7 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antikörper
Immunohistochemistry (IHC) 76 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 26 Antikörper

General

Antigen Fas Ligand (TNF Superfamily, Member 6) (FASL) Antikörper
Reaktivität Human
(403), (174), (89), (36), (7), (5), (5), (3), (3), (2), (1), (1)
Wirt Maus
(241), (175), (49), (32), (29), (8), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser FASL Antikörper ist konjugiert mit PE
(44), (29), (26), (11), (11), (8), (8), (8), (8), (7), (7), (7), (7), (7), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Mass Cytometry (CyTOF)
(298), (244), (111), (97), (80), (75), (38), (34), (28), (28), (13), (12), (10), (10), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 7 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FASL Antikörper

Target Details FASL Anwendungsinformationen Handhabung ProductDetails: References for anti-FASL antibody (ABIN2663099) Bilder
Reinigung The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Klon NOK-1
Isotyp IgG1 kappa

Target Details FASL

Produktdetails anti-FASL Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-FASL antibody (ABIN2663099) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD178 (FASL Antibody Abstract)
Hintergrund CD178 is a 38-42 kD type II glycoprotein also known as Fas ligand and CD95L. CD178 belongs to the TNF superfamily and is expressed on activated T lymphocytes, NK cells, monocytes, and granulocytes. CD178 is also expressed on parenchymal cells of the retina and cornea, retinal pigment epithelial cells, and testis. The extracellular region of FasL can be cleaved by matrix metalloproteinases (MMPs) to give rise to a 26 kD soluble protein. CD178 binds to CD95, a member of the TNFR superfamily, to induce apoptosis. CD95/CD95L interactions play an important role in the maintenance of peripheral tolerance and survival.
Pathways Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

Anwendungsinformationen

Produktdetails anti-FASL Antikörper Target Details FASL Handhabung ProductDetails: References for anti-FASL antibody (ABIN2663099) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FASL Antikörper Target Details FASL Anwendungsinformationen ProductDetails: References for anti-FASL antibody (ABIN2663099) Bilder zurück nach oben
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

ProductDetails: References for anti-FASL antibody (ABIN2663099)

Produktdetails anti-FASL Antikörper Target Details FASL Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Li, DAlessio, Pober: "Lipopolysaccharide can trigger a cathepsin B-dependent programmed death response in human endothelial cells." in: The American journal of pathology, Vol. 175, Issue 3, pp. 1124-35, 2009

Strauss, Bergmann, Whiteside: "Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1469-80, 2009

Andreola, Rivoltini, Castelli, Huber, Perego, Deho, Squarcina, Accornero, Lozupone, Lugini, Stringaro, Molinari, Arancia, Gentile, Parmiani, Fais: "Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles." in: The Journal of experimental medicine, Vol. 195, Issue 10, pp. 1303-16, 2002

Herr, Posovsky, Böhler, Debatin: "mAb33 from transduction laboratories specifically binds human CD95-L." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 129-30, 2000

Bossi, Griffiths: "Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells." in: Nature medicine, Vol. 5, Issue 1, pp. 90-6, 1999

Kayagaki, Kawasaki, Ebata, Ohmoto, Ikeda, Inoue, Yoshino, Okumura, Yagita: "Metalloproteinase-mediated release of human Fas ligand." in: The Journal of experimental medicine, Vol. 182, Issue 6, pp. 1777-83, 1996

Tanaka, Suda, Takahashi, Nagata: "Expression of the functional soluble form of human fas ligand in activated lymphocytes." in: The EMBO journal, Vol. 14, Issue 6, pp. 1129-35, 1995

Bilder

Produktdetails anti-FASL Antikörper Target Details FASL Anwendungsinformationen Handhabung ProductDetails: References for anti-FASL antibody (ABIN2663099) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-FASL Antikörper (Fas Ligand (TNF Superfamily, Member 6))  (PE) (ABIN2663099) anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) antibody (PE)