Cylindromatosis (Turban Tumor Syndrome) ELISA Kits (CYLD)
Auf finden Sie aktuell 9 Cylindromatosis (Turban Tumor Syndrome) (CYLD) ELISA Kits von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CYLD Antikörper (79) und CYLD Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 99 CYLD Produkte verfügbar.
2010013M14Rik, 2900009M21Rik, BRSS, C130039D01Rik, CDMT, cyld, CYLD1, CYLDI, EAC, LRRGT00003, MFT, MFT1, mKIAA0849, Rp1, Rp1h, SBS, TEM, USPL2

Weitere ELISA Kits für CYLD Interaktionspartner

Zebrafish Cylindromatosis (Turban Tumor Syndrome) (CYLD) Interaktionspartner

  1. The crystal structures representing the catalytic states of zebrafish CYLD for Met1 (zeige DNMT1 ELISA Kits)- and Lys63-linked Ub chains and two distinct precatalytic states for Met1 (zeige DNMT1 ELISA Kits)-linked chains are presented.

Mouse (Murine) Cylindromatosis (Turban Tumor Syndrome) (CYLD) Interaktionspartner

  1. TLR4 (zeige TLR4 ELISA Kits) activates CASPASE-8 (zeige CASP8 ELISA Kits) to cleave and remove the deubiquitinase cylindromatosis (CYLD) in a TRIF (zeige RNF138 ELISA Kits)- and RIPK1 (zeige RIPK1 ELISA Kits)-dependent manner to disable necroptosis in macrophages.

  2. CYLD contributes to the transdifferentiation of adventitial fibroblasts via deubiquitinating Nox4 (zeige NOX4 ELISA Kits) and may play a role in vascular remodeling.

  3. this study shows that by polarization of the T cell cytokine response, CYLD can favor the development of allergic airway disease

  4. Our findings underscore a critical tumor-suppressing role for functional intestinal epithelial CYLD in colitis-associated carcinogenesis

  5. Deubiquitinase CYLD negatively regulates MyD88 (zeige MYD88 ELISA Kits)-mediated signaling by directly interacting with MyD88 (zeige MYD88 ELISA Kits) and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63-linked polyubiquitination of MyD88 (zeige MYD88 ELISA Kits) at lysine 231.

  6. CYLD interrupts the ERK (zeige EPHB2 ELISA Kits)- and p38 (zeige CRK ELISA Kits)-/AP-1 (zeige JUN ELISA Kits) and c-Myc (zeige MYC ELISA Kits) pathways to suppress Nrf2 (zeige NFE2L2 ELISA Kits)-operated antioxidative capacity, thereby enhancing oxidative stress in the heart.

  7. Our data demonstrate that inefficient negative selection in the thymus of CYLD(ex7/8) mice result from a defect in mTEC maturation.

  8. The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.

  9. Data show that the in utero death of NF-NF (zeige NFASC ELISA Kits)-kappaB (zeige NFKB1 ELISA Kits) essential modulator (NEMO (zeige IKBKG ELISA Kits)) and cylindromatosis protein double mutant mice is mediated by TNF (zeige TNF ELISA Kits) receptor 1 (TNFR1 (zeige TNFRSF1A ELISA Kits)) signaling and can be rescued by TNFR1 (zeige TNFRSF1A ELISA Kits) deficiency.

  10. CYLD is a central regulator of apoptotic cell death in murine hepatocytes by controlling NF-kappaB (zeige NFKB1 ELISA Kits) dependent anti-apoptotic signaling.

Human Cylindromatosis (Turban Tumor Syndrome) (CYLD) Interaktionspartner

  1. The data reveal SPATA2 as a high-affinity binding partner of CYLD and HOIP (zeige RNF31 ELISA Kits), and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB (zeige NFKB1 ELISA Kits) signaling.

  2. The current investigations identified a subset of HPV-positive HNSCCs with mutations in the genes TRAF3 (zeige TRAF3 ELISA Kits) (tumor necrosis factor (zeige TNF ELISA Kits) receptor-associated factor 3) and CYLD (cylindromatosis lysine 63 deubiquitinase). Defects in TRAF3 (zeige TRAF3 ELISA Kits) and CYLD correlated with the activation of transcriptional factor nuclear factor kappaB, episomal HPV status of tumors, and improved patient survival.

  3. The predicted PUB domain in the N-terminus of SPATA2 interacts with the USP domain of CYLD and SPATA2 is required for recruitment of CYLD to the TNF-alpha receptor-associated signaling complexes.

  4. STAT3 (zeige STAT3 ELISA Kits) and miR (zeige MLXIP ELISA Kits)-181b control each other's expression in a positive feedback loop that regulates SFCs via CYLD pathway.

  5. CYLD Promotes TNF-alpha (zeige TNF ELISA Kits)-Induced Cell Necrosis Mediated by RIP-1 in Human Lung Cancer Cells

  6. Low CYLD expression is associated with hepatocellular carcinoma.

  7. miR20a directly repressed the expression of CYLD, leading to activation of the NFkappaB (zeige NFKB1 ELISA Kits) pathway and the downstream targets, livin (zeige BIRC7 ELISA Kits) and survivin (zeige BIRC5 ELISA Kits), which potentially induced GC chemoresistance.

  8. Data show that cylindromatosis (CYLD) overexpression and livin (zeige BIRC7 ELISA Kits) knockdown might improve gemcitabine chemosensitivity by decreasing autophagy and increasing apoptosis in bladder cancer (BCa (zeige BLNK ELISA Kits)) cells.

  9. aberrantly expressed miR (zeige MLXIP ELISA Kits)-130b may regulate cell apoptosis and proliferation of human gastric cancer cells via CYLD, which appears to be a promising therapeutic target for gastric cancer

  10. These results demonstrate the involvement of histone deacetylases in the down regulation of Cyld expression in hepatocellular carcinoma cells.

CYLD Antigen-Profil

Beschreibung des Gens

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with CYLD

  • cylindromatosis (turban tumor syndrome) (CYLD) Elisa Kit
  • cylindromatosis (turban tumor syndrome), a (cylda) Elisa Kit
  • ubiquitin carboxyl-terminal hydrolase CYLD (LOC100362727) Elisa Kit
  • cylindromatosis (turban tumor syndrome) (Cyld) Elisa Kit
  • 2010013M14Rik Elisa Kit
  • 2900009M21Rik Elisa Kit
  • BRSS Elisa Kit
  • C130039D01Rik Elisa Kit
  • CDMT Elisa Kit
  • cyld Elisa Kit
  • CYLD1 Elisa Kit
  • CYLDI Elisa Kit
  • EAC Elisa Kit
  • LRRGT00003 Elisa Kit
  • MFT Elisa Kit
  • MFT1 Elisa Kit
  • mKIAA0849 Elisa Kit
  • Rp1 Elisa Kit
  • Rp1h Elisa Kit
  • SBS Elisa Kit
  • TEM Elisa Kit
  • USPL2 Elisa Kit

Bezeichner auf Proteinebene für CYLD

cylindromatosis (turban tumor syndrome) , probable ubiquitin carboxyl-terminal hydrolase CYLD-like , ubiquitin carboxyl-terminal hydrolase CYLD , deubiquitinating enzyme CYLD , ubiquitin thioesterase CYLD , ubiquitin thiolesterase CYLD , ubiquitin-specific-processing protease CYLD , probable ubiquitin carboxyl-terminal hydrolase CYLD , retinitis pigmentosa 1 homolog , ubiquitin specific peptidase like 2

100050308 Equus caballus
556823 Danio rerio
100467467 Ailuropoda melanoleuca
100547998 Meleagris gallopavo
100362727 Rattus norvegicus
74256 Mus musculus
312937 Rattus norvegicus
1540 Homo sapiens
611649 Canis lupus familiaris
536421 Bos taurus
415725 Gallus gallus
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