anti-CYLD (CYLD) Antikörper

anti-Cylindromatosis (Turban Tumor Syndrome) Antikörper (CYLD)
Auf finden Sie aktuell 79 Cylindromatosis (Turban Tumor Syndrome) (CYLD) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CYLD Kits (9) und CYLD Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 99 CYLD Produkte verfügbar.
2010013M14Rik, 2900009M21Rik, BRSS, C130039D01Rik, CDMT, cyld, CYLD1, CYLDI, EAC, LRRGT00003, MFT, MFT1, mKIAA0849, Rp1, Rp1h, SBS, TEM, USPL2

Meistgesuchte Reaktivitäten zu anti-CYLD (CYLD) Antikörper

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anti-Rat (Rattus) CYLD Antikörper:

anti-Mouse (Murine) CYLD Antikörper:

anti-Human CYLD Antikörper:

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Am meisten referenzierte anti-CYLD Antikörper

  1. Mouse (Murine) Polyclonal CYLD Primary Antibody für ELISA, WB - ABIN190823 : Massoumi, Chmielarska, Hennecke, Pfeifer, Fässler: Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. in Cell 2006 (PubMed)

  2. Human Polyclonal CYLD Primary Antibody für ICC, IF - ABIN252428 : Moranta, Regueiro, March, Llobet, Margareto, Larrarte, Larrate, Garmendia, Bengoechea: Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells. in Infection and immunity 2010 (PubMed)

Weitere Antikörper gegen CYLD Interaktionspartner

Zebrafish Cylindromatosis (Turban Tumor Syndrome) (CYLD) Interaktionspartner

  1. The crystal structures representing the catalytic states of zebrafish CYLD for Met1 (zeige DNMT1 Antikörper)- and Lys63-linked Ub chains and two distinct precatalytic states for Met1 (zeige DNMT1 Antikörper)-linked chains are presented.

Mouse (Murine) Cylindromatosis (Turban Tumor Syndrome) (CYLD) Interaktionspartner

  1. TLR4 (zeige TLR4 Antikörper) activates CASPASE-8 (zeige CASP8 Antikörper) to cleave and remove the deubiquitinase cylindromatosis (CYLD) in a TRIF (zeige RNF138 Antikörper)- and RIPK1 (zeige RIPK1 Antikörper)-dependent manner to disable necroptosis in macrophages.

  2. CYLD contributes to the transdifferentiation of adventitial fibroblasts via deubiquitinating Nox4 (zeige NOX4 Antikörper) and may play a role in vascular remodeling.

  3. this study shows that by polarization of the T cell cytokine response, CYLD can favor the development of allergic airway disease

  4. Our findings underscore a critical tumor-suppressing role for functional intestinal epithelial CYLD in colitis-associated carcinogenesis

  5. Deubiquitinase CYLD negatively regulates MyD88 (zeige MYD88 Antikörper)-mediated signaling by directly interacting with MyD88 (zeige MYD88 Antikörper) and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63-linked polyubiquitination of MyD88 (zeige MYD88 Antikörper) at lysine 231.

  6. CYLD interrupts the ERK (zeige EPHB2 Antikörper)- and p38 (zeige CRK Antikörper)-/AP-1 (zeige JUN Antikörper) and c-Myc (zeige MYC Antikörper) pathways to suppress Nrf2 (zeige NFE2L2 Antikörper)-operated antioxidative capacity, thereby enhancing oxidative stress in the heart.

  7. Our data demonstrate that inefficient negative selection in the thymus of CYLD(ex7/8) mice result from a defect in mTEC maturation.

  8. The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.

  9. Data show that the in utero death of NF-NF (zeige NFASC Antikörper)-kappaB (zeige NFKB1 Antikörper) essential modulator (NEMO (zeige IKBKG Antikörper)) and cylindromatosis protein double mutant mice is mediated by TNF (zeige TNF Antikörper) receptor 1 (TNFR1 (zeige TNFRSF1A Antikörper)) signaling and can be rescued by TNFR1 (zeige TNFRSF1A Antikörper) deficiency.

  10. CYLD is a central regulator of apoptotic cell death in murine hepatocytes by controlling NF-kappaB (zeige NFKB1 Antikörper) dependent anti-apoptotic signaling.

Human Cylindromatosis (Turban Tumor Syndrome) (CYLD) Interaktionspartner

  1. The data reveal SPATA2 (zeige SPATA2 Antikörper) as a high-affinity binding partner of CYLD and HOIP (zeige RNF31 Antikörper), and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB (zeige NFKB1 Antikörper) signaling.

  2. The current investigations identified a subset of HPV-positive HNSCCs with mutations in the genes TRAF3 (zeige TRAF3 Antikörper) (tumor necrosis factor (zeige TNF Antikörper) receptor-associated factor 3) and CYLD (cylindromatosis lysine 63 deubiquitinase). Defects in TRAF3 (zeige TRAF3 Antikörper) and CYLD correlated with the activation of transcriptional factor nuclear factor kappaB, episomal HPV status of tumors, and improved patient survival.

  3. The predicted PUB domain in the N-terminus of SPATA2 interacts with the USP domain of CYLD and SPATA2 is required for recruitment of CYLD to the TNF-alpha receptor-associated signaling complexes.

  4. STAT3 (zeige STAT3 Antikörper) and miR (zeige MLXIP Antikörper)-181b control each other's expression in a positive feedback loop that regulates SFCs via CYLD pathway.

  5. CYLD Promotes TNF-alpha (zeige TNF Antikörper)-Induced Cell Necrosis Mediated by RIP-1 (zeige UQCRFS1 Antikörper) in Human Lung Cancer Cells

  6. Low CYLD expression is associated with hepatocellular carcinoma.

  7. miR20a directly repressed the expression of CYLD, leading to activation of the NFkappaB (zeige NFKB1 Antikörper) pathway and the downstream targets, livin (zeige BIRC7 Antikörper) and survivin (zeige BIRC5 Antikörper), which potentially induced GC chemoresistance.

  8. Data show that cylindromatosis (CYLD) overexpression and livin (zeige BIRC7 Antikörper) knockdown might improve gemcitabine chemosensitivity by decreasing autophagy and increasing apoptosis in bladder cancer (BCa (zeige BLNK Antikörper)) cells.

  9. aberrantly expressed miR (zeige MLXIP Antikörper)-130b may regulate cell apoptosis and proliferation of human gastric cancer cells via CYLD, which appears to be a promising therapeutic target for gastric cancer

  10. These results demonstrate the involvement of histone deacetylases in the down regulation of Cyld expression in hepatocellular carcinoma cells.

CYLD Antigen-Profil

Beschreibung des Gens

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with CYLD

  • cylindromatosis (turban tumor syndrome) (CYLD) Antikörper
  • cylindromatosis (turban tumor syndrome), a (cylda) Antikörper
  • ubiquitin carboxyl-terminal hydrolase CYLD (LOC100362727) Antikörper
  • cylindromatosis (turban tumor syndrome) (Cyld) Antikörper
  • 2010013M14Rik Antikörper
  • 2900009M21Rik Antikörper
  • BRSS Antikörper
  • C130039D01Rik Antikörper
  • CDMT Antikörper
  • cyld Antikörper
  • CYLD1 Antikörper
  • CYLDI Antikörper
  • EAC Antikörper
  • LRRGT00003 Antikörper
  • MFT Antikörper
  • MFT1 Antikörper
  • mKIAA0849 Antikörper
  • Rp1 Antikörper
  • Rp1h Antikörper
  • SBS Antikörper
  • TEM Antikörper
  • USPL2 Antikörper

Bezeichner auf Proteinebene für CYLD

cylindromatosis (turban tumor syndrome) , probable ubiquitin carboxyl-terminal hydrolase CYLD-like , ubiquitin carboxyl-terminal hydrolase CYLD , deubiquitinating enzyme CYLD , ubiquitin thioesterase CYLD , ubiquitin thiolesterase CYLD , ubiquitin-specific-processing protease CYLD , probable ubiquitin carboxyl-terminal hydrolase CYLD , retinitis pigmentosa 1 homolog , ubiquitin specific peptidase like 2

100050308 Equus caballus
556823 Danio rerio
100467467 Ailuropoda melanoleuca
100547998 Meleagris gallopavo
100362727 Rattus norvegicus
74256 Mus musculus
312937 Rattus norvegicus
1540 Homo sapiens
611649 Canis lupus familiaris
536421 Bos taurus
415725 Gallus gallus
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