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anti-CYLD (CYLD) Antikörper

Bezeichnung:
anti-Cylindromatosis (Turban Tumor Syndrome) Antikörper (CYLD)
Auf www.antikoerper-online.de finden Sie aktuell 78 Cylindromatosis (Turban Tumor Syndrome) (CYLD) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CYLD Proteine (7) und CYLD Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 94 CYLD Produkte verfügbar.
Synonyme:
2010013M14Rik, 2900009M21Rik, BRSS, C130039D01Rik, CDMT, cyld, CYLD1, CYLDI, EAC, LRRGT00003, MFT, MFT1, mKIAA0849, Rp1, Rp1h, SBS, TEM, USPL2

Meistgesuchte Reaktivitäten zu anti-CYLD (CYLD) Antikörper

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anti-Rat (Rattus) CYLD Antikörper:

anti-Mouse (Murine) CYLD Antikörper:

anti-Human CYLD Antikörper:

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Am meisten referenzierte anti-CYLD Antikörper

  1. Mouse (Murine) Polyclonal CYLD Primary Antibody für WB - ABIN374832 : Massoumi, Chmielarska, Hennecke, Pfeifer, Fässler: Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. in Cell 2006 (PubMed)

  2. Human Polyclonal CYLD Primary Antibody für ICC, IF - ABIN252428 : Moranta, Regueiro, March, Llobet, Margareto, Larrarte, Larrate, Garmendia, Bengoechea: Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells. in Infection and immunity 2010 (PubMed)

Weitere Antikörper gegen CYLD Interaktionspartner

Zebrafish Cylindromatosis (Turban Tumor Syndrome) (CYLD) Interaktionspartner

  1. The crystal structures representing the catalytic states of zebrafish CYLD for Met1 (zeige DNMT1 Antikörper)- and Lys63-linked Ub chains and two distinct precatalytic states for Met1 (zeige DNMT1 Antikörper)-linked chains are presented.

Mouse (Murine) Cylindromatosis (Turban Tumor Syndrome) (CYLD) Interaktionspartner

  1. Our findings underscore a critical tumor-suppressing role for functional intestinal epithelial CYLD in colitis-associated carcinogenesis

  2. Deubiquitinase CYLD negatively regulates MyD88 (zeige MYD88 Antikörper)-mediated signaling by directly interacting with MyD88 (zeige MYD88 Antikörper) and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63-linked polyubiquitination of MyD88 (zeige MYD88 Antikörper) at lysine 231.

  3. CYLD interrupts the ERK (zeige EPHB2 Antikörper)- and p38 (zeige CRK Antikörper)-/AP-1 (zeige JUN Antikörper) and c-Myc (zeige MYC Antikörper) pathways to suppress Nrf2 (zeige NFE2L2 Antikörper)-operated antioxidative capacity, thereby enhancing oxidative stress in the heart.

  4. Our data demonstrate that inefficient negative selection in the thymus of CYLD(ex7/8) mice result from a defect in mTEC maturation.

  5. The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.

  6. Data show that the in utero death of NF-NF (zeige NFASC Antikörper)-kappaB (zeige NFKB1 Antikörper) essential modulator (NEMO (zeige IKBKG Antikörper)) and cylindromatosis protein double mutant mice is mediated by TNF (zeige TNF Antikörper) receptor 1 (TNFR1 (zeige TNFRSF1A Antikörper)) signaling and can be rescued by TNFR1 (zeige TNFRSF1A Antikörper) deficiency.

  7. CYLD is a central regulator of apoptotic cell death in murine hepatocytes by controlling NF-kappaB (zeige NFKB1 Antikörper) dependent anti-apoptotic signaling.

  8. In contrast to full-length CYLD, the immune function of short splice variant CYLD (sCYLD) is insufficiently described. To explore sCYLD's function in infection, investigated whether dendritic cell-specific sCYLD regulates the pathogenesis of listeriosis.

  9. The ciliary function of CYLD is partially attributed to its deconjugation of the polyubiquitin (zeige UBB Antikörper) chain from centrosomal protein of 70 kDa (Cep70 (zeige CEP70 Antikörper)), a requirement for Cep70 (zeige CEP70 Antikörper) to interact with gamma-tubulin (zeige TUBG1 Antikörper) and localize at the centrosome.

  10. CYLD negatively regulates nontypeable Haemophilus influenzae-induced IL-8 (zeige IL8 Antikörper) expression via MKP-1 (zeige DUSP1 Antikörper)-dependent inhibition of ERK (zeige EPHB2 Antikörper).

Human Cylindromatosis (Turban Tumor Syndrome) (CYLD) Interaktionspartner

  1. Low CYLD expression is associated with hepatocellular carcinoma.

  2. miR20a directly repressed the expression of CYLD, leading to activation of the NFkappaB (zeige NFKB1 Antikörper) pathway and the downstream targets, livin (zeige BIRC7 Antikörper) and survivin (zeige BIRC5 Antikörper), which potentially induced GC chemoresistance.

  3. Data show that cylindromatosis (CYLD) overexpression and livin (zeige BIRC7 Antikörper) knockdown might improve gemcitabine chemosensitivity by decreasing autophagy and increasing apoptosis in bladder cancer (BCa (zeige BLNK Antikörper)) cells.

  4. aberrantly expressed miR (zeige MLXIP Antikörper)-130b may regulate cell apoptosis and proliferation of human gastric cancer cells via CYLD, which appears to be a promising therapeutic target for gastric cancer

  5. These results demonstrate the involvement of histone deacetylases in the down regulation of Cyld expression in hepatocellular carcinoma cells.

  6. Novel CYLD germline mutations c.1821_1826+1delinsCT/L607Ffs*9, c.2666A>T/p.D889V and c.2712delT/p.905Kfs*8 were identified in unrelated Brooke-Spiegler Syndrome patients.

  7. Study founds the levels of CYLD and SMAD7 (zeige SMAD7 Antikörper) significantly decreased in oral squamous cell carcinoma (OSSC) cells and proposes a model that CYLD suppresses OSCC metastases through SMAD7 (zeige SMAD7 Antikörper). Downregulation of CYLD appears to directly contribute to the distal metastases of primary OSCC and subsequently poor prognosis.

  8. Haplotype analysis was performed for the patients with multiple familial trichoepithelioma type 1, patients with familial cylindromatosis and a patient with Brooke-Spiegler syndrome, all of whom carry the same heterozygous nonsense CYLD mutation.

  9. Ultraviolet radiation induced CYLD translocation from the cytoplasm to microtubules, posttranslational modification and degradation in a proteasome-independent manner.

  10. Deubiquitinase CYLD negatively regulates MyD88 (zeige MYD88 Antikörper)-mediated signaling by directly interacting with MyD88 (zeige MYD88 Antikörper) and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63-linked polyubiquitination of MyD88 (zeige MYD88 Antikörper) at lysine 231.

CYLD Antigen-Profil

Beschreibung des Gens

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with CYLD

  • cylindromatosis (turban tumor syndrome) (CYLD) Antikörper
  • cylindromatosis (turban tumor syndrome), a (cylda) Antikörper
  • ubiquitin carboxyl-terminal hydrolase CYLD (LOC100362727) Antikörper
  • cylindromatosis (turban tumor syndrome) (Cyld) Antikörper
  • 2010013M14Rik Antikörper
  • 2900009M21Rik Antikörper
  • BRSS Antikörper
  • C130039D01Rik Antikörper
  • CDMT Antikörper
  • cyld Antikörper
  • CYLD1 Antikörper
  • CYLDI Antikörper
  • EAC Antikörper
  • LRRGT00003 Antikörper
  • MFT Antikörper
  • MFT1 Antikörper
  • mKIAA0849 Antikörper
  • Rp1 Antikörper
  • Rp1h Antikörper
  • SBS Antikörper
  • TEM Antikörper
  • USPL2 Antikörper

Bezeichner auf Proteinebene für CYLD

cylindromatosis (turban tumor syndrome) , probable ubiquitin carboxyl-terminal hydrolase CYLD-like , ubiquitin carboxyl-terminal hydrolase CYLD , deubiquitinating enzyme CYLD , ubiquitin thioesterase CYLD , ubiquitin thiolesterase CYLD , ubiquitin-specific-processing protease CYLD , probable ubiquitin carboxyl-terminal hydrolase CYLD , retinitis pigmentosa 1 homolog , ubiquitin specific peptidase like 2

GENE ID SPEZIES
100050308 Equus caballus
556823 Danio rerio
100467467 Ailuropoda melanoleuca
100547998 Meleagris gallopavo
100362727 Rattus norvegicus
74256 Mus musculus
312937 Rattus norvegicus
1540 Homo sapiens
611649 Canis lupus familiaris
536421 Bos taurus
415725 Gallus gallus
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