anti-Human Caspase 3 Antikörper für Fluorescence Microscopy

Recommended Caspase 3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Antikörper
  • CC3
  • CG14902
  • Cas3
  • Casp 3
  • Casp3
  • Caspase-3
  • DECAY
  • Decay
  • Dmel\\CG14902
  • Drosophila executioner caspase related to Apopain/Yama
  • caspase 3
  • caspase-3
  • CG7788
  • DRICE
  • Dmel\\CG7788
  • DrICE
  • DrIce
  • Drice
  • ICE
  • crice
  • drICE
  • drIce
  • drice
  • ice
  • A830040C14Rik
  • AC-3
  • Apopain
  • CPP32
  • Lice
  • Yama
  • mldy
  • CPP32B
  • SCA-1
  • xcpp32
  • caspase 3, apoptosis-related cysteine peptidase
  • death executioner caspase related to Apopain/Yama
  • CG7788 gene product from transcript CG7788-RA
  • caspase 3
  • CASP3
  • decay
  • Ice
  • Casp3
  • casp3
Epitop
AA 1-219
41
32
27
24
22
21
19
19
16
15
12
12
11
10
10
10
9
7
5
5
5
5
5
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
566
305
254
48
47
38
29
28
24
20
18
18
18
12
9
8
7
4
2
2
Wirt
Maus
458
161
19
4
2
Klonalität
Monoklonal
Konjugat
Dieser Caspase 3 Antikörper ist unkonjugiert
27
24
19
14
9
9
9
6
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
Applikation
Fluorescence Microscopy (FM), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
482
237
219
147
95
77
55
51
44
29
28
13
9
9
7
5
4
3
2
2
2
2
2
2
1
1
1
1
1
Optionen
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Bilder

Produktnummer ABIN967901
146,73 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN967902 FM IP IHC WB Mouse IgG2a AA 1-219 Anmelden zum Anzeigen 19-Caspase 6

anti-Caspase 3 Antikörper für Fluorescence Microscopy mit den meisten Publikationen

Ähnliche anti-Caspase 3 Antikörper

Applikation / Reaktivität Human
BioImaging (BI) 1 Antikörper
Blocking Reagent (BR) 2 Antikörper
Cellular Assay (CA) 1 Antikörper
Chromatin Immunoprecipitation (ChIP) 2 Antikörper
Cytometry by Time of Flight (CyTOF) 4 Antikörper
Dot Blot (DB) 18 Antikörper
Electron Microscopy (EM) 2 Antikörper
ELISA 170 Antikörper
ELISA (Capture) 3 Antikörper
ELISpot (Capture) (ELISPOT (Capture)) 2 Antikörper
Enzyme Immunoassay (EIA) 7 Antikörper
Flow Cytometry (FACS) 95 Antikörper
Fluorescence Microscopy (FM) 2 Antikörper
Immunoassay (IA) 1 Antikörper
Immunochromatography (IC) 7 Antikörper
Immunocytochemistry (ICC) 37 Antikörper
Immunofluorescence (IF) 47 Antikörper
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 6 Antikörper

General

Antigen Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Antikörper
Epitop AA 1-219
(41), (32), (27), (24), (22), (21), (19), (19), (16), (15), (12), (12), (11), (10), (10), (10), (9), (7), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(566), (305), (254), (48), (47), (38), (29), (28), (24), (20), (18), (18), (18), (12), (9), (8), (7), (4), (2), (2)
Wirt Maus
(458), (161), (19), (4), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Caspase 3 Antikörper ist unkonjugiert
(27), (24), (19), (14), (9), (9), (9), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Fluorescence Microscopy (FM), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(482), (237), (219), (147), (95), (77), (55), (51), (44), (29), (28), (13), (9), (9), (7), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Caspase 3 Antikörper

Target Details Caspase 3 Anwendungsinformationen Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN967901) Bilder
Produktmerkmale 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols.
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human CPP32 aa. 1-219
Klon 19-Caspase
Isotyp IgG2a

Target Details Caspase 3

Produktdetails anti-Caspase 3 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN967901) Bilder zurück nach oben
Antigen
Andere Bezeichnung Caspase-3 (CASP3 Antibody Abstract)
Hintergrund Apoptosis, a selective process of genetically programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptotic cells are characterized by loss of cell volume, plasma membrane blebbing, nuclear condensation, chromatin aggregation, and endonucleocytic degradation of DNA into nucleosomal fragments. Caspase-3 (CPP32, Yama, apopain) is a member of the family of cysteine proteases which includes interleukin-1beta converting enzyme (ICE) and C. elegans protein, Ced-3. An apoptotic signal such as granzyme B of cytotoxic T-cells (CTLs) or ICE-like proteases induces the intracellular cleavage of Caspase-3 from the inactive pro-form (32 kDa) to the active form which consists of the p20, p17, and p12 subunits. The active form of Caspase-3 cleaves several other apoptotic proteins including proteins such as DNA Fragmentation Factor (DFF). Apoptosis can be inhibited by coexpression of Bcl-2 as well as inhibitors of Caspase-3 or other members of the family of cysteine proteases. This antibody recognizes the human pro-form (inactive) of Caspase-3 at 32 kDa. In addition, it has been reported to recognize the active form of Caspase-3 at 20-21 kD in apoptotic cell lysates.
Synonyms: CPP32
Molekulargewicht 32 kDa
Forschungsgebiet Apoptosis/Necrosis, Autophagy
Pathways Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation

Anwendungsinformationen

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN967901) Bilder zurück nach oben
Kommentare

Related Products: ABIN968537, ABIN967389, ABIN967299

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Anwendungsinformationen ProductDetails: References for anti-Caspase 3 antibody (ABIN967901) Bilder zurück nach oben
Format Liquid
Konzentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store undiluted at -20° C.

ProductDetails: References for anti-Caspase 3 antibody (ABIN967901)

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Takemoto, Nagai, Miyawaki, Miura: "Spatio-temporal activation of caspase revealed by indicator that is insensitive to environmental effects." in: The Journal of cell biology, Vol. 160, Issue 2, pp. 235-43, 2003

Li, Chen, Sinogeeva, Gorospe, Wersto, Chrest, Barnes, Liu: "Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49504-10, 2002

Donoghue, Baden, Lauder, Sobolewski, Pringle: "Immunohistochemical localization of caspase-3 correlates with clinical outcome in B-cell diffuse large-cell lymphoma." in: Cancer research, Vol. 59, Issue 20, pp. 5386-91, 1999

Scaffidi, Fulda, Srinivasan, Friesen, Li, Tomaselli, Debatin, Krammer, Peter: "Two CD95 (APO-1/Fas) signaling pathways." in: The EMBO journal, Vol. 17, Issue 6, pp. 1675-87, 1998

Allgemeine Veröffentlichungen

Fernandes-Alnemri, Litwack, Alnemri: "CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme." in: The Journal of biological chemistry, Vol. 269, Issue 49, pp. 30761-4, 1995

Bilder

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Anwendungsinformationen Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN967901) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Caspase 3 Antikörper (Caspase 3, Apoptosis-Related Cysteine Peptidase) (AA 1-219) (ABIN967901) Western blot analysis of Caspase-3 on a Jurkat cell lysate (Human T-cell leukemia, AT...