anti-Human Caspase 3 Antikörper für ELISA (Capture)

Recommended Caspase 3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Antikörper
  • CC3
  • CG14902
  • Cas3
  • Casp 3
  • Casp3
  • Caspase-3
  • DECAY
  • Decay
  • Dmel\\CG14902
  • Drosophila executioner caspase related to Apopain/Yama
  • caspase 3
  • caspase-3
  • CG7788
  • DRICE
  • Dmel\\CG7788
  • DrICE
  • DrIce
  • Drice
  • ICE
  • crice
  • drICE
  • drIce
  • drice
  • ice
  • A830040C14Rik
  • AC-3
  • Apopain
  • CPP32
  • Lice
  • Yama
  • mldy
  • CPP32B
  • SCA-1
  • xcpp32
  • caspase 3, apoptosis-related cysteine peptidase
  • death executioner caspase related to Apopain/Yama
  • CG7788 gene product from transcript CG7788-RA
  • caspase 3
  • CASP3
  • decay
  • Ice
  • Casp3
  • casp3
Reaktivität
Human
566
305
254
48
47
38
29
28
24
20
18
18
18
12
9
8
7
4
2
2
Wirt
Maus
458
161
19
4
2
Klonalität
Monoklonal
Konjugat
Dieser Caspase 3 Antikörper ist konjugiert mit Biotin
26
24
19
14
9
9
9
6
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
Applikation
ELISA (Capture), Immunoprecipitation (IP), Western Blotting (WB)
482
238
219
147
95
77
55
51
44
29
28
13
9
9
7
5
4
2
2
2
2
2
2
2
2
1
1
1
1
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Bilder

Produktnummer ABIN2660890
201,88 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2666066 BR ELISA (Capture) ELISPOT (Capture) Mouse IgG2a, IgG2a kappa Anmelden zum Anzeigen 4-1-18 6
1 ABIN2666067 BR ELISA (Capture) ELISPOT (Capture) Mouse IgG2a, IgG2a kappa Anmelden zum Anzeigen 4-1-18 6

anti-Caspase 3 Antikörper für ELISA (Capture) mit den meisten Publikationen

Ähnliche anti-Caspase 3 Antikörper

Applikation / Reaktivität Human
BioImaging (BI) 1 Antikörper
Blocking Reagent (BR) 2 Antikörper
Cellular Assay (CA) 1 Antikörper
Chromatin Immunoprecipitation (ChIP) 2 Antikörper
Cytometry by Time of Flight (CyTOF) 4 Antikörper
Dot Blot (DB) 18 Antikörper
Electron Microscopy (EM) 2 Antikörper
ELISA 170 Antikörper
ELISA (Capture) 3 Antikörper
ELISpot (Capture) (ELISPOT (Capture)) 2 Antikörper
Enzyme Immunoassay (EIA) 7 Antikörper
Flow Cytometry (FACS) 95 Antikörper
Fluorescence Microscopy (FM) 2 Antikörper
Immunoassay (IA) 1 Antikörper
Immunochromatography (IC) 7 Antikörper
Immunocytochemistry (ICC) 37 Antikörper
Immunofluorescence (IF) 47 Antikörper
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 6 Antikörper

General

Antigen Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Antikörper
Reaktivität Human
(566), (305), (254), (48), (47), (38), (29), (28), (24), (20), (18), (18), (18), (12), (9), (8), (7), (4), (2), (2)
Wirt Maus
(458), (161), (19), (4), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Caspase 3 Antikörper ist konjugiert mit Biotin
(26), (24), (19), (14), (9), (9), (9), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation ELISA (Capture), Immunoprecipitation (IP), Western Blotting (WB)
(482), (238), (219), (147), (95), (77), (55), (51), (44), (29), (28), (13), (9), (9), (7), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Caspase 3 Antikörper

Target Details Caspase 3 Anwendungsinformationen Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN2660890) Bilder
Kreuzreaktivität (Details) recognizes 32 kD pro-caspase-3 and 17 kD cleaved caspase-3
Reinigung The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Klon 4-1-18
Isotyp IgG2a, IgG2a kappa

Target Details Caspase 3

Produktdetails anti-Caspase 3 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN2660890) Bilder zurück nach oben
Antigen
Andere Bezeichnung Caspase-3 (CASP3 Antibody Abstract)
Hintergrund Caspase 3 (also known as cpp32, Apopain, Yama, and PARP cleavage protease) is a member of the peptidase family C14. This cytoplasmic caspase functions as a heterotetramer and has two isoforms (one acts as a dominant negative inhibitor). The pro-form of this caspase is approximately 32 kD. Caspase 3 is involved in the caspase activation cascade responsible for apoptosis execution. This caspase cleaves/activates SREBPs, Caspase 6, Caspase 7, and Caspase 9. Caspase 3 is inhibited by c-IAP1, c-IAP2, XIAP, survivin, and Livin and activated by Caspase 6, -8 , and -10, granzyme B, Apaf-1 by cleavage into large p17 and small p12 subunits. Active heterodimers form between the large p17 subunit and small p11 subunit of Caspase 7 and vice versa. Caspase 3 has been shown to cleave PARP, huntingtin, androgen receptor, atrophin-1, DNA- PKcs, D4-GDI, hnRNPs C1/C2, U1snRNP, PKC delta, ATM, fodrin, gelsolin, ICAD, RIP, X-IAP, STAT1, topoisomerase I, vimentin, Rb, lamin B, mdm2, and β-catenin. The 4-1-18 monoclonal antibody has been shown to be useful for Western blotting of human caspase 3 (32 kD pro-caspase and 17 kD cleaved caspase).
Forschungsgebiet Apoptosis/Necrosis, Autophagy
Pathways Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation

Anwendungsinformationen

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN2660890) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Anwendungsinformationen ProductDetails: References for anti-Caspase 3 antibody (ABIN2660890) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

ProductDetails: References for anti-Caspase 3 antibody (ABIN2660890)

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Woo, Hakem, Furlonger, Hakem, Duncan, Sasaki, Bouchard, Lu, Wu, Paige, Mak: "Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity." in: Nature immunology, Vol. 4, Issue 10, pp. 1016-22, 2003

Slee, Adrain, Martin: "Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 10, pp. 7320-6, 2001

Goldberg, Nicholson, Rasper, Kalchman, Koide, Graham, Bromm, Kazemi-Esfarjani, Thornberry, Vaillancourt, Hayden: "Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract." in: Nature genetics, Vol. 13, Issue 4, pp. 442-9, 1996

Fernandes-Alnemri, Armstrong, Krebs, Srinivasula, Wang, Bullrich, Fritz, Trapani, Tomaselli, Litwack, Alnemri: "In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 15, pp. 7464-9, 1996

Bilder

Produktdetails anti-Caspase 3 Antikörper Target Details Caspase 3 Anwendungsinformationen Handhabung ProductDetails: References for anti-Caspase 3 antibody (ABIN2660890) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Caspase 3 Antikörper (Caspase 3, Apoptosis-Related Cysteine Peptidase)  (Biotin) (ABIN2660890) anti-Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) antibody (Biotin)