anti-Human Caspase 12 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended Caspase 12 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Caspase 12 (Gene/pseudogene) (CASP12) Antikörper
  • CASP12P1
  • CASP-12
  • caspase 12 (gene/pseudogene)
  • CASP12
Epitop
AA 165-193, Center
8
8
7
7
4
2
1
1
Reaktivität
Human
24
6
4
Wirt
Kaninchen
23
2
Klonalität
Polyklonal
Konjugat
Dieser Caspase 12 Antikörper ist unkonjugiert
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
23
13
13
8
7
3
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN655966
$ 324.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN3042658 IHC (p) WB Rabbit IgG AA 71-84, N-Term Anmelden zum Anzeigen Polyclonal 2
1 ABIN5535971 FACS IF IHC (p) WB Rabbit Ig Fraction AA 165-193 Anmelden zum Anzeigen Polyclonal
1 ABIN5573756 IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal

General

Antigen Caspase 12 (Gene/pseudogene) (CASP12) Antikörper
Epitop AA 165-193, Center
(8), (8), (7), (7), (4), (2), (1), (1)
Reaktivität Human
(24), (6), (4)
Wirt Kaninchen
(23), (2)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Dieser Caspase 12 Antikörper ist unkonjugiert
(1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(23), (13), (13), (8), (7), (3), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Caspase 12 Antikörper

Target Details Caspase 12 Anwendungsinformationen Handhabung Bilder
Spezifität This CASP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the Central region of human CASP12.
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This CASP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-193 AA from the Central region of human CASP12.
Klon RB31705
Isotyp Ig

Target Details Caspase 12

Produktdetails anti-Caspase 12 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung CASP12 (CASP12 Antibody Abstract)
Hintergrund Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.
Synonyms: CASP12,Inactive caspase-12,
Molekulargewicht 38907 Da
Gen-ID 120329
UniProt Q6UXS9
Forschungsgebiet Cell Structure
Pathways Apoptose, ER-Nucleus Signaling, Unfolded protein response

Anwendungsinformationen

Produktdetails anti-Caspase 12 Antikörper Target Details Caspase 12 Handhabung Bilder zurück nach oben
Applikationshinweise WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50, IF = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Caspase 12 Antikörper Target Details Caspase 12 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 0.39 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months

Bilder

Produktdetails anti-Caspase 12 Antikörper Target Details Caspase 12 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 165-193), (Center) antibody (ABIN655966) CASP12 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane...
Immunohistochemistry (IHC) image for anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 165-193), (Center) antibody (ABIN655966) CASP12 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin...
Flow Cytometry (FACS) image for anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 165-193), (Center) antibody (ABIN655966) CASP12 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) c...
Immunofluorescence (IF) image for anti-Caspase 12 (Gene/pseudogene) (CASP12) (AA 165-193), (Center) antibody (ABIN655966) Confocal immunofluorescent analysis of CASP12 Antibody (Center) with 293 cell followe...