Die folgenden Gennamen und Gensymbole werden für Antigen zeta-Chain (TCR) Associated Protein Kinase 70kDa über verschiedene Spezies hinweg verwendet:

zeta-chain (TCR) associated protein kinase 70kDa (ZAP70), zeta-chain (TCR) associated protein kinase (Zap70), zeta-chain (TCR) associated protein kinase 70kDa (zap70), tyrosine-protein kinase zap-70 (Smp_149470)

Zu den weiteren Synonymen zählen:

SRK, STD, TZK, ZAP-70, FLJ17670, FLJ17679, Srk, mur, 70kDa, mrtle, AI327364, MGC108902, zap70, MGC80670, MGC88962, ZAP70

Auf Proteinebene tauchen folgende Bezeichner für Antigen zeta-Chain (TCR) Associated Protein Kinase 70kDa auf:

zeta-chain associated protein kinase 70kDa – syk-related tyrosine kinase – zeta-chain associated protein kinase, 70kD – tyrosine-protein kinase ZAP-70 – 70 kDa zeta-associated protein – syk-related protein tyrosine kinase – zeta-chain (TCR) associated protein kinase 70 – zeta-chain (TCR) associated protein kinase 70kDa – tyrosine-protein kinase zap-70 – tyrosine-protein kinase ZAP-70-like

zeta-Chain (TCR) Associated Protein Kinase 70kDa erfüllt eine Reihe von Funktionen:

ATP binding – non-membrane spanning protein tyrosine kinase activity – nucleotide binding – protein binding – transferase activity – kinase activity – phosphotyrosine binding – protein kinase activity – protein tyrosine kinase activity – molecular_function

zeta-Chain (TCR) Associated Protein Kinase 70kDa spielt in den folgenden Prozessen eine Rolle:

immune response – positive regulation of T cell differentiation – positive thymic T cell selection – protein amino acid phosphorylation – protein kinase cascade – signal transduction – T cell receptor signaling pathway – beta selection – intracellular protein kinase cascade – intracellular signaling pathway – negative thymic T cell selection – peptidyl-tyrosine phosphorylation – positive regulation of alpha-beta T cell differentiation – positive regulation of alpha-beta T cell proliferation – positive regulation of calcium-mediated signaling – protein amino acid autophosphorylation – thymic T cell selection – biological_process – intracellular signaling cascade

zeta-Chain (TCR) Associated Protein Kinase 70kDa ist wie folgt lokalisiert:

T cell receptor complex – cytoplasm – cytosol – immunological synapse – membrane – plasma membrane – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology