Die folgenden Gennamen und Gensymbole werden für Antigen serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 über verschiedene Spezies hinweg verwendet:

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2), nexin-1 (PN-1), serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (serpine2)

Zu den weiteren Synonymen zählen:

GDN, PI7, PN1, PNI, PI-7, PN-1, DKFZp686A13110, SERPINE2, MGC143011

Auf Proteinebene tauchen folgende Bezeichner für Antigen serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 auf:

glia-derived nexin – serpin E2 – protease nexin I – OTTHUMP00000203766 – peptidase inhibitor 7 – glial-derived neurite promoting factor – plasminogen activator inhibitor type 1, member 2 – serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 – nexin-1 – serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 – protease nexin-1 – glia-derived nexin-like

serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 erfüllt eine Reihe von Funktionen:

glycosaminoglycan binding – heparin binding – peptidase inhibitor activity – protein binding – receptor binding – serine-type endopeptidase inhibitor activity

serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 spielt in den folgenden Prozessen eine Rolle:

cell differentiation – multicellular organismal development – negative regulation of blood coagulation – negative regulation of plasminogen activation – negative regulation of platelet aggregation – negative regulation of protein maturation by peptide bond cleavage – negative regulation of proteolysis – nervous system development – positive regulation of astrocyte differentiation – regulation of cell migration

serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 ist wie folgt lokalisiert:

cytosol – extracellular matrix – extracellular region – extracellular space – extrinsic to external side of plasma membrane – neuromuscular junction – platelet alpha granule

Quelle: NCBI Entrez Gene, Gene Ontology