Die folgenden Gennamen und Gensymbole werden für Antigen beta-Catenin über verschiedene Spezies hinweg verwendet:

catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), catenin (cadherin associated protein), beta 1 (Ctnnb1), catenin (cadherin-associated protein), beta 1 (ctnnb1), armadillo (arm), beta-catenin protein (beta-catenin), beta-catenin (Cibeta-catenin), catenin (cadherin-associated protein), beta 1, 88kDa (ctnnb1), beta-catenin (LOC576711), beta-catenin (Ctnnb1), Catenin beta-1 (ctnb1), beta-catenin (CNA03500), beta-catenin (LOC100533383)

Zu den weiteren Synonymen zählen:

CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1)G0410, l(1)arm, t12687 ALR Dm, DmelCG11579, CG11579, beta-catenin, ctnnb1, MGC79992, MGC132060, Cibeta-catenin, CTNNB1, MGC52601, LOC576711, Ctnnb1, MGC139922

Auf Proteinebene tauchen folgende Bezeichner für Antigen beta-Catenin auf:

beta-catenin – catenin beta-1 – OTTHUMP00000209288 – OTTMUSP00000017750 – catenin (cadherin-associated protein), beta 1 – armadillo, isoform D – CG11579-PD – arm-PD – Armadillo/beta-catenin – beta-Catenin – armadillo – catenin – b-catenin – Armadillo(Arm)/beta-catenin – armadillo, isoform A – CG11579-PA – arm-PA – armadillo, isoform C – CG11579-PC – arm-PC – armadillo, isoform B – CG11579-PB – arm-PB – armadillo, isoform E – CG11579-PE – arm-PE – catenin beta – catenin (cadherin associated protein), beta 1, 88kDa – beta-catenin protein – Catenin beta – catenin (cadherin-associated protein), beta 1, 88kDa – Catenin beta-1

beta-Catenin erfüllt eine Reihe von Funktionen:

I-SMAD binding – alpha-catenin binding – androgen receptor binding – cadherin binding – chromatin binding – double-stranded DNA binding – kinase binding – promoter binding – protein C-terminus binding – protein phosphatase binding – signal transducer activity – transcription coactivator activity – transcription factor activity – transcription factor binding – DNA binding – binding – protein binding – transcription activator activity – cytoskeletal protein binding

beta-Catenin spielt in den folgenden Prozessen eine Rolle:

T cell differentiation in the thymus – Wnt receptor signaling pathway through beta-catenin – androgen receptor signaling pathway – anterior/posterior axis specification – apoptosis – bone resorption – camera-type eye morphogenesis – cell fate specification – cell maturation – cell-cell adhesion – cell-matrix adhesion – cellular protein localization – dorsal/ventral axis specification – ectoderm development – embryonic arm morphogenesis – embryonic digit morphogenesis – embryonic hindlimb morphogenesis – endodermal cell fate commitment – epithelial to mesenchymal transition – forebrain development – gastrulation with mouth forming second – glial cell fate determination – heart development – hemopoiesis – lung development – morphogenesis of embryonic epithelium – negative regulation of chondrocyte differentiation – negative regulation of osteoclast differentiation – negative regulation of transcription from RNA polymerase II promoter – odontogenesis of dentine-containing tooth – pancreas development – patterning of blood vessels – positive regulation of MAPKKK cascade – positive regulation of epithelial cell differentiation – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of heparan sulfate proteoglycan biosynthetic process – positive regulation of osteoblast differentiation – proximal/distal pattern formation – regulation of cell proliferation – regulation of centriole-centriole cohesion – skeletal system development – synapse organization – synaptic transmission – synaptic vesicle transport – thymus development – Wnt receptor signaling pathway – cell adhesion – cell differentiation – cell fate determination – cell morphogenesis involved in differentiation – cell proliferation – cellular process – dorsal/ventral pattern formation – endoderm formation – epithelial cell differentiation involved in prostate gland development – negative regulation of cell differentiation – negative regulation of transcription, DNA-dependent – osteoclast differentiation – positive regulation of epithelial cell proliferation involved in prostate gland development – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – positive regulation of transcription, DNA-dependent – regulation of cell differentiation – regulation of epithelial cell differentiation – regulation of osteoblast differentiation – regulation of osteoclast differentiation – regulation of transcription – regulation of transcription, DNA-dependent – transcription – embryonic axis specification – liver development – branch fusion, open tracheal system – cell morphogenesis – compound eye morphogenesis – compound eye retinal cell programmed cell death – cuticle pattern formation – cytoskeletal anchoring at plasma membrane – delamination – dorsal closure – establishment or maintenance of cell polarity – germ-line stem cell division – imaginal disc-derived wing expansion – nervous system development – neuroblast development – neuroblast fate determination – oocyte localization during germarium-derived egg chamber formation – oogenesis – ovarian follicle cell development – photoreceptor cell differentiation – positive regulation of JNK cascade – protein localization – regulation of cell shape – somatic stem cell maintenance – ventral furrow formation – wing disc morphogenesis – zonula adherens assembly – Schwann cell proliferation – midgut development – myoblast differentiation – protein heterooligomerization – response to cadmium ion – response to cytokine stimulus – response to estrogen stimulus – response to hormone stimulus – response to organic cyclic substance – microautophagy – protein targeting to vacuole – vacuole inheritance

beta-Catenin ist wie folgt lokalisiert:

Axin-APC-beta-catenin-GSK3B complex – Z disc – apical junction complex – apical part of cell – basolateral plasma membrane – beta-catenin destruction complex – beta-catenin-TCF7L2 complex – catenin complex – centrosome – cytoplasm – cytoskeleton – cytosol – fascia adherens – lamellipodium – lateral plasma membrane – membrane fraction – microvillus membrane – nucleus – plasma membrane – transcription factor complex – adherens junction – cell junction – cell projection membrane – cell-cell adherens junction – cell-cell junction – membrane – cell cortex – desmosome – intercalated disc – microvillus – apical plasma membrane – apicolateral plasma membrane – spot adherens junction – zonula adherens – dendritic shaft – neuron projection – protein complex – synapse – fungal-type vacuole

Quelle: NCBI Entrez Gene, Gene Ontology