Die folgenden Gennamen und Gensymbole werden für Antigen Xeroderma Pigmentosum, Complementation Group B über verschiedene Spezies hinweg verwendet:

excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3)

Zu den weiteren Synonymen zählen:

XPB, BTF2, GTF2H, RAD25, TFIIH

Auf Proteinebene tauchen folgende Bezeichner für Antigen Xeroderma Pigmentosum, Complementation Group B auf:

excision repair cross-complementing rodent repair deficiency, complementation group 3 – xeroderma pigmentosum, complementation group B

Xeroderma Pigmentosum, Complementation Group B erfüllt eine Reihe von Funktionen:

3'-5' DNA helicase activity – ATP binding – ATP-dependent DNA helicase activity – ATPase activity – RNA polymerase II carboxy-terminal domain kinase activity – damaged DNA binding – helicase activity – hydrolase activity – nucleotide binding – protein C-terminus binding – protein N-terminus binding – protein kinase activity – transcription factor binding

Xeroderma Pigmentosum, Complementation Group B spielt in den folgenden Prozessen eine Rolle:

DNA topological change – RNA elongation from RNA polymerase II promoter – UV protection – cell cycle checkpoint – hair cell differentiation – induction of apoptosis – interspecies interaction between organisms – nucleotide-excision repair, DNA damage removal – nucleotide-excision repair, DNA duplex unwinding – nucleotide-excision repair, DNA incision – positive regulation of transcription from RNA polymerase II promoter – protein localization – regulation of transcription – response to DNA damage stimulus – response to oxidative stress – transcription initiation from RNA polymerase II promoter – transcription-coupled nucleotide-excision repair

Xeroderma Pigmentosum, Complementation Group B ist wie folgt lokalisiert:

holo TFIIH complex – nucleoplasm – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology