Die folgenden Gennamen und Gensymbole werden für Antigen X-ray Repair, Complementing Defective, Repair in Chinese Hamster über verschiedene Spezies hinweg verwendet:

X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5)

Zu den weiteren Synonymen zählen:

KU80, KUB2, Ku86, NFIV, KARP1, KARP-1, FLJ39089

Auf Proteinebene tauchen folgende Bezeichner für Antigen X-ray Repair, Complementing Defective, Repair in Chinese Hamster auf:

ATP-dependent DNA helicase II – OTTHUMP00000164061 – OTTHUMP00000206791 – Ku autoantigen, 80kDa – DNA repair protein XRCC5 – Ku86 autoantigen related protein 1 – X-ray repair, complementing defective, repair in Chinese hamster – X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kD)

X-ray Repair, Complementing Defective, Repair in Chinese Hamster erfüllt eine Reihe von Funktionen:

ATP binding – ATP-dependent DNA helicase activity – DNA binding – double-stranded telomeric DNA binding – helicase activity – hydrolase activity – nucleotide binding – promoter binding – protein C-terminus binding

X-ray Repair, Complementing Defective, Repair in Chinese Hamster spielt in den folgenden Prozessen eine Rolle:

double-strand break repair via nonhomologous end joining – initiation of viral infection – provirus integration – response to DNA damage stimulus – telomere maintenance

X-ray Repair, Complementing Defective, Repair in Chinese Hamster ist wie folgt lokalisiert:

chromosome – nuclear telomere cap complex – nucleoplasm – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology