Die folgenden Gennamen und Gensymbole werden für Antigen X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 über verschiedene Spezies hinweg verwendet:

X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6), ATP-dependent DNA helicase II, 70 kDa subunit (Bm1_41430), ATP-dependent DNA helicase II, 70 kDa subunit (LOC100351956), X-ray repair complementing defective repair in Chinese hamster cells 6 (xrcc6)

Zu den weiteren Synonymen zählen:

ML8, KU70, TLAA, CTC75, CTCBF, G22P1, XRCC6, MGC82304, DKFZp459H0114

Auf Proteinebene tauchen folgende Bezeichner für Antigen X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 auf:

ATP-dependent DNA helicase II, 70 kDa subunit – OTTHUMP00000199333 – OTTHUMP00000199349 – Ku autoantigen, 70kDa – Ku autoantigen p70 subunit – thyroid-lupus autoantigen p70 – CTC box binding factor 75 kDa subunit – thyroid autoantigen 70kD (Ku antigen) – thyroid autoantigen 70kDa (Ku antigen) – X-ray repair complementing defective repair in Chinese hamster cells 6 – X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) – ATP-dependent DNA helicase 2 subunit 1

X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 erfüllt eine Reihe von Funktionen:

ATP binding – ATP-dependent DNA helicase activity – DNA binding – double-stranded telomeric DNA binding – helicase activity – hydrolase activity – nucleotide binding – promoter binding – protein C-terminus binding – transcription activator activity – binding

X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 spielt in den folgenden Prozessen eine Rolle:

DNA ligation – V(D)J recombination – double-strand break repair via nonhomologous end joining – initiation of viral infection – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of neurogenesis – positive regulation of transcription, DNA-dependent – provirus integration – response to DNA damage stimulus – response to ionizing radiation – telomere maintenance

X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 ist wie folgt lokalisiert:

DNA-dependent protein kinase-DNA ligase 4 complex – chromosome – cytoplasm – membrane fraction – nuclear telomere cap complex – nucleoplasm – nucleus – transcription factor complex

Quelle: NCBI Entrez Gene, Gene Ontology