Die folgenden Gennamen und Gensymbole werden für Antigen X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 über verschiedene Spezies hinweg verwendet:

X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4)

Auf Proteinebene tauchen folgende Bezeichner für Antigen X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 auf:

X-ray repair cross complementing protein 4 – DNA repair protein XRCC4 – X-ray repair, complementing defective, repair in Chinese hamster

X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 erfüllt eine Reihe von Funktionen:

DNA binding – ligase activity – protein C-terminus binding

X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 spielt in den folgenden Prozessen eine Rolle:

DNA ligation during DNA repair – T cell differentiation in the thymus – central nervous system development – double-strand break repair via nonhomologous end joining – immunoglobulin V(D)J recombination – in utero embryonic development – initiation of viral infection – isotype switching – negative regulation of neuron apoptosis – positive regulation of fibroblast proliferation – positive regulation of ligase activity – positive regulation of neurogenesis – pro-B cell differentiation – provirus integration – response to DNA damage stimulus – response to X-ray – response to gamma radiation

X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 ist wie folgt lokalisiert:

DNA ligase IV complex – DNA-dependent protein kinase-DNA ligase 4 complex – condensed chromosome – cytosol – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology