Die folgenden Gennamen und Gensymbole werden für Antigen V-Raf Murine Sarcoma Viral Oncogene Homolog B1 über verschiedene Spezies hinweg verwendet:

v-raf murine sarcoma viral oncogene homolog B1 (BRAF), v-raf murine sarcoma viral oncogene homolog B1 (Braf), v-raf murine sarcoma viral oncogene homolog B1 (braf), v-raf murine sarcoma viral oncogene homolog B1 (LOC100219601)

Zu den weiteren Synonymen zählen:

BRAF1, RAFB1, B-RAF1, FLJ95109, MGC126806, MGC138284, RMIL, C-RMIL, B-Raf, braf1, rafb1, b-raf1, BRAF

Auf Proteinebene tauchen folgende Bezeichner für Antigen V-Raf Murine Sarcoma Viral Oncogene Homolog B1 auf:

B-Raf – 94 kDa B-raf protein – murine sarcoma viral (v-raf) oncogene homolog B1 – B-Raf proto-oncogene serine/threonine-protein kinase (p94) – serine/threonine-protein kinase B-raf – proto-oncogene B-Raf – proto-oncogene c-Rmil – serine/threonine kinase – rmil serine/threonine-protein kinase – serine/threonine-protein kinase Rmil – B-Raf proto-oncogene serine/threonine-protein kinase – serine/threonine protein kinase BRAF – v-raf murine sarcoma viral oncogene homolog B1 – B-raf protein – serine/threonine-protein kinase B-raf-like

V-Raf Murine Sarcoma Viral Oncogene Homolog B1 erfüllt eine Reihe von Funktionen:

ATP binding – diacylglycerol binding – metal ion binding – nucleotide binding – protein binding – protein serine/threonine kinase activity – receptor signaling protein activity – transferase activity – zinc ion binding – MAP kinase kinase kinase activity – mitogen-activated protein kinase kinase binding – protein heterodimerization activity – kinase activity – protein kinase activity – protein tyrosine kinase activity

V-Raf Murine Sarcoma Viral Oncogene Homolog B1 spielt in den folgenden Prozessen eine Rolle:

anti-apoptosis – organ morphogenesis – protein amino acid phosphorylation – small GTPase mediated signal transduction – MAPKKK cascade – negative regulation of neuron apoptosis – positive regulation of ERK1 and ERK2 cascade – protein heterooligomerization – response to cAMP – response to peptide hormone stimulus – signal transduction – intracellular signaling cascade

V-Raf Murine Sarcoma Viral Oncogene Homolog B1 ist wie folgt lokalisiert:

cytoplasm – nucleus – plasma membrane – membrane fraction – soluble fraction – synaptosome

Quelle: NCBI Entrez Gene, Gene Ontology