Die folgenden Gennamen und Gensymbole werden für Antigen V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) über verschiedene Spezies hinweg verwendet:

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4), v-erb-a erythroblastic leukemia viral oncogene homolog 4a (avian) (erbb4a), v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (erbb4), v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (Erbb4), v-erb-a erythroblastic leukemia viral oncogene homolog 4 (ERBB4), v-erb-a erythroblastic leukemia viral oncogene homolog 4 (erbb4), receptor tyrosine-protein kinase ErbB-4 (Tsp_13582)

Zu den weiteren Synonymen zählen:

erbb4, si:ch211-227n20.1, HER4, MGC138404, p180erbB4, Her4

Auf Proteinebene tauchen folgende Bezeichner für Antigen V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) auf:

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) – v-erb-a erythroblastic leukemia viral oncogene homolog 4a – erbb4c – v-erb-a erythroblastic leukemia viral oncogene homolog 4 – receptor tyrosine-protein kinase erbB-4-like – receptor tyrosine-protein kinase erbB-4 – tyrosine kinase-type cell surface receptor HER4 – avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4 – c-erbB-4 – OTTMUSP00000030425 – OTTMUSP00000030426 – OTTMUSP00000030427 – avian erythroblastosis oncogene B 4 – proto-oncogene-like protein c-ErbB-4 – receptor tyrosine kinase – ovarian receptor tyrosine kinase erbB4 precusor – receptor tyrosine kinase ErbB4 – receptor tyrosine-protein kinase ErbB-4

V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) erfüllt eine Reihe von Funktionen:

ATP binding – nucleotide binding – protein binding – receptor activity – transferase activity – transmembrane receptor protein tyrosine kinase activity – kinase activity – protein kinase activity – protein tyrosine kinase activity – receptor signaling protein tyrosine kinase activity

V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) spielt in den folgenden Prozessen eine Rolle:

cell fate commitment – cell proliferation – heart development – nervous system development – protein amino acid phosphorylation – signal transduction – transmembrane receptor protein tyrosine kinase signaling pathway – peptidyl-tyrosine phosphorylation – positive regulation of anti-apoptosis – positive regulation of cell migration – positive regulation of epithelial cell proliferation – positive regulation of glucose import – positive regulation of synaptic transmission, GABAergic – regulation of transcription – surfactant homeostasis – synapse maturation – transcription – mammary gland development – odontogenesis – response to drug – response to hydrogen peroxide – response to progesterone stimulus – telencephalon development

V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) ist wie folgt lokalisiert:

basolateral plasma membrane – integral to membrane – membrane – caveola – cytoplasm – membrane raft – nucleus – plasma membrane – postsynaptic density

Quelle: NCBI Entrez Gene, Gene Ontology