Die folgenden Gennamen und Gensymbole werden für Antigen V-Akt Murine Thymoma Viral Oncogene Homolog 2 über verschiedene Spezies hinweg verwendet:

v-akt murine thymoma viral oncogene homolog 2 (AKT2), v-akt murine thymoma viral oncogene homolog 2 (Akt2), v-akt murine thymoma viral oncogene homolog 2 (akt2)

Zu den weiteren Synonymen zählen:

PKBB, PRKBB, PKBBETA, RAC-BETA, AKT2, cb945, prkbb, v-akt2, pkbbeta, rac-beta

Auf Proteinebene tauchen folgende Bezeichner für Antigen V-Akt Murine Thymoma Viral Oncogene Homolog 2 auf:

AKT2 kinase – rac protein kinase beta – Murine thymoma viral (v-akt) homolog-2 – RAC-beta serine/threonine-protein kinase – PKB beta – RAC-PK-beta – protein kinase Akt-2 – protein kinase B beta – protein kinase B, beta – thymoma viral proto-oncogene 2 – RAC protein kinase beta RAC-PK beta – murine thymoma viral (v-akt) oncogene homolog 2 – v-akt murine thymoma viral oncogene homolog 2 – RAC-beta serine/threonine-protein kinase-like – serine/threonine protein kinase

V-Akt Murine Thymoma Viral Oncogene Homolog 2 erfüllt eine Reihe von Funktionen:

ATP binding – nucleotide binding – protein binding – protein serine/threonine kinase activity – transferase activity – kinase activity – protein kinase activity

V-Akt Murine Thymoma Viral Oncogene Homolog 2 spielt in den folgenden Prozessen eine Rolle:

insulin receptor signaling pathway – negative regulation of plasma membrane long-chain fatty acid transport – positive regulation of fatty acid beta-oxidation – positive regulation of glucose import – positive regulation of glucose metabolic process – positive regulation of glycogen biosynthetic process – protein amino acid phosphorylation – protein modification process – cellular response to chemical stimulus – cellular response to hormone stimulus – cellular response to insulin stimulus – negative regulation of RNA splicing – negative regulation of apoptosis – negative regulation of caspase activity – positive regulation of cell migration – positive regulation of gene expression – positive regulation of nitric oxide biosynthetic process – positive regulation of peptidyl-serine phosphorylation – positive regulation of positive chemotaxis – positive regulation of protein amino acid phosphorylation – positive regulation of signal transduction – positive regulation of sodium ion transport – positive regulation of transcription from RNA polymerase II promoter – protein kinase B signaling cascade – regulation of JNK cascade – response to insulin stimulus – response to muscle activity – response to nutrient levels – response to osmotic stress

V-Akt Murine Thymoma Viral Oncogene Homolog 2 ist wie folgt lokalisiert:

cytosol – insulin-responsive compartment – lamellipodium – microsome – mitochondrion – nucleoplasm – nucleus – plasma membrane – soluble fraction – vesicle

Quelle: NCBI Entrez Gene, Gene Ontology