Die folgenden Gennamen und Gensymbole werden für Antigen V-Akt Murine Thymoma Viral Oncogene Homolog 1 über verschiedene Spezies hinweg verwendet:

v-akt murine thymoma viral oncogene homolog 1 (AKT1), v-akt murine thymoma viral oncogene homolog 1 (Akt1), v-akt murine thymoma viral oncogene homolog 1 (akt1), Akt1, isoform A (Akt1)

Zu den weiteren Synonymen zählen:

AKT, PKB, RAC, PRKBA, MGC99656, PKB-ALPHA, RAC-ALPHA, Akt, pkb, xAct, akt-1, v-akt, v-akt1, AKT1, AKT/PKB, D-Akt, DAKT1, DAKT1/PKB, DPKB, DRAC-PK, DRAC-PK66; DRAC-PK85, Dakt, PKB/AKT, PKB/dAKT, RacPK, dAKT/dPKB, dAkt/PKB, l(3)04226, l(3)89Bq, DmelCG4006, CG4006

Auf Proteinebene tauchen folgende Bezeichner für Antigen V-Akt Murine Thymoma Viral Oncogene Homolog 1 auf:

AKT1 kinase – protein kinase B – rac protein kinase alpha – RAC-alpha serine/threonine-protein kinase – PKB – RAC-PK-alpha – thymoma viral proto-oncogene 1 – RAC protein kinase alpha RAC-PK alpha – murine thymoma viral (v-akt) oncogene homolog 1 – v-akt murine thymoma viral oncogene-like protein 1 – serine/threonine protein kinase – Akt – xAkt – PKB alpha – protein kinase Akt-1 – protein kinase B, alpha – v-akt murine thymoma viral oncogene homolog 1 – RAC-alpha serine/threonine-protein kinase-like – Akt1, isoform A – CG4006-PA – Akt1-PA – related to the A and C kinases – related to PKA to PKC protein kinases – Akt1, isoform B – CG4006-PB – Akt1-PB – Akt1, isoform C – CG4006-PC – Akt1-PC

V-Akt Murine Thymoma Viral Oncogene Homolog 1 erfüllt eine Reihe von Funktionen:

ATP binding – enzyme binding – identical protein binding – nitric-oxide synthase regulator activity – nucleotide binding – phosphatidylinositol-3,4,5-trisphosphate binding – phosphatidylinositol-3,4-bisphosphate binding – protein serine/threonine kinase activity – transferase activity – kinase activity – protein binding – protein kinase activity – phosphoinositide binding

V-Akt Murine Thymoma Viral Oncogene Homolog 1 spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – activation of pro-apoptotic gene products – activation-induced cell death of T cells – anagen – apoptotic mitochondrial changes – blood vessel development – carbohydrate metabolic process – carbohydrate transport – cell projection organization – germ cell development – glucose transport – inflammatory response – insulin receptor signaling pathway – insulin-like growth factor receptor signaling pathway – intracellular signaling cascade – negative regulation of cell size – negative regulation of fatty acid beta-oxidation – negative regulation of plasma membrane long-chain fatty acid transport – negative regulation of protein kinase activity – peptidyl-serine phosphorylation – placenta development – positive regulation of cell growth – positive regulation of cellular protein metabolic process – positive regulation of cyclin-dependent protein kinase activity during G1/S – positive regulation of fat cell differentiation – positive regulation of glucose import – positive regulation of glucose metabolic process – positive regulation of glycogen biosynthetic process – positive regulation of lipid biosynthetic process – positive regulation of multicellular organism growth – positive regulation of nitric oxide biosynthetic process – positive regulation of nitric-oxide synthase activity – positive regulation of proteasomal ubiquitin-dependent protein catabolic process – positive regulation of sodium ion transport – protein amino acid autophosphorylation – protein catabolic process – protein import into nucleus, translocation – protein kinase B signaling cascade – protein modification process – protein ubiquitination – regulation of establishment of protein localization – regulation of survival gene product expression – regulation of translation – response to UV-A – response to fluid shear stress – response to food – response to heat – response to hormone stimulus – anti-apoptosis – apoptosis – cellular response to insulin stimulus – glycogen biosynthetic process – glycogen cell development involved in embryonic placenta development – glycogen metabolic process – intracellular signaling pathway – labyrinthine layer blood vessel development – maternal placenta development – negative regulation of JNK cascade – negative regulation of apoptosis – nervous system development – phosphorylation – positive regulation of cyclin-dependent protein kinase activity involved in G1/S – positive regulation of establishment of protein localization in plasma membrane – protein amino acid phosphorylation – regulation of cell migration – regulation of glycogen biosynthetic process – regulation of neuron projection development – regulation of protein localization – signal transduction – translation – chitin-based embryonic cuticle biosynthetic process – lipid storage – open tracheal system development – positive regulation of cell size – positive regulation of organ growth – regulation of cell shape – regulation of cell size – regulation of multicellular organism growth – regulation of organ growth – regulation of protein import into nucleus

V-Akt Murine Thymoma Viral Oncogene Homolog 1 ist wie folgt lokalisiert:

cytoplasm – cytoskeleton – cytosol – lamellipodium – nucleoplasm – nucleus – plasma membrane – spindle – microtubule cytoskeleton – soluble fraction – cell surface

Quelle: NCBI Entrez Gene, Gene Ontology