Die folgenden Gennamen und Gensymbole werden für Antigen Ubiquitin über verschiedene Spezies hinweg verwendet:

ubiquitin B (UBB), ubiquitin B (Ubb), Ubiquitin-63E (Ubi-p63E), Ubiquitin-5E (Ubi-p5E), transmembrane and ubiquitin-like domain containing 2 (tmub2), (CR11700), polyubiquitin (LOC100194618), polyubiquitin containing 7 ubiquitin monomers (LOC100282068)

Zu den weiteren Synonymen zählen:

MGC8385, FLJ25987, Ubc, Ubb2, Uba52, Rps27a, AL033289, CG11624, DmelCG11624, DmUb, Ub, ubi, Ubi-p, ubi-p63E, Ubi-P63e, ubi63E, Ubi63E, Ubi63p, Ubip, Ubiq, Ubp, UBC, CG18282, CG32744, CR32744, DmelCG32744, ubiquitin, si:dz180g5.5, si:busm1-180g5.5, UBB, Ubiquitin, CG11700, ESTS:143G11T, ESTS:199A6T, anon-sts41, poly-ub, DmelCR11700, LOC100194618, UBIQ, LOC100282068

Auf Proteinebene tauchen folgende Bezeichner für Antigen Ubiquitin auf:

ubiquitin B – polyubiquitin B – OTTHUMP00000064960 – OTTHUMP00000064961 – polyubiquitin-B – OTTMUSP00000006062 – OTTMUSP00000045396 – Ubiquitin-63E, isoform B – CG11624-PB – Ubi-p63E-PB – polyubiquitin – ubiquitin – Ubiquitin-polymeric – Ubiquitin-63E, isoform C – CG11624-PC – Ubi-p63E-PC – Ubiquitin-63E, isoform A – CG11624-PA – Ubi-p63E-PA – Ubiquitin-5E – CG32744-PA – Ubi-p5E-PA – transmembrane and ubiquitin-like domain containing 2 – polyubiquitin containing 7 ubiquitin monomers

Ubiquitin erfüllt eine Reihe von Funktionen:

protein binding – transcription regulator activity

Ubiquitin spielt in den folgenden Prozessen eine Rolle:

ER-associated protein catabolic process – anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process – anti-apoptosis – apoptosis – axon guidance – cell cycle – induction of apoptosis by extracellular signals – long-term strengthening of neuromuscular junction – negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle – positive regulation of transcription – positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle – protein ubiquitination – regulation of synaptic plasticity – cellular process – chromatin organization – phagocytosis, engulfment – protein modification process – regulation of transcription, DNA-dependent – response to heat – response to stress – ribosome biogenesis – ubiquitin-dependent protein catabolic process

Ubiquitin ist wie folgt lokalisiert:

cytoplasm – cytosol – nucleoplasm – nucleus – polytene chromosome band – integral to membrane

Quelle: NCBI Entrez Gene, Gene Ontology