Die folgenden Gennamen und Gensymbole werden für Antigen Ubiquitin-Conjugating Enzyme E2I über verschiedene Spezies hinweg verwendet:

ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) (UBE2I), ubiquitin-conjugating enzyme E2I (ube2i), ubiquitin-conjugating enzyme E2L (UBE2L), ubiquitin-conjugating enzyme E2I (LOC100358924), ubiquitin-conjugating enzyme E2I (Ube2i), ubiquitin-conjugating enzyme E2I (UBE2I)

Zu den weiteren Synonymen zählen:

P18, UBC9, C358B7.1, ubc9, zUbc9, Ubce9, Ubce2i, 5830467E05Rik, F830028O17Rik, UBE2I

Auf Proteinebene tauchen folgende Bezeichner für Antigen Ubiquitin-Conjugating Enzyme E2I auf:

ubiquitin-conjugating enzyme E2I – OTTHUMP00000198126 – OTTHUMP00000198127 – SUMO-1-protein ligase – ubiquitin carrier protein – ubiquitin-protein ligase E2I – ubiquitin conjugating enzyme 9 – ubiquitin-conjugating enzyme UbcE2A – ubiquitin-like protein SUMO-1 conjugating enzyme – ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9) – ubc9.1 – ubiquitin-conjugating enzyme 9 – ubiquitin-conjugating enzyme E2L – SUMO-conjugating enzyme UBC9 – SUMO-protein ligase – ubiquitin-protein ligase I – ubiquitin carrier protein 9 – ubiquitin carrier protein I – SUMO-1 conjugating enzyme – ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)

Ubiquitin-Conjugating Enzyme E2I erfüllt eine Reihe von Funktionen:

ATP binding – HLH domain binding – enzyme binding – ligase activity – nucleotide binding – small conjugating protein ligase activity – specific transcriptional repressor activity – SUMO ligase activity – bHLH transcription factor binding – protein C-terminus binding – protein binding – ubiquitin-protein ligase activity

Ubiquitin-Conjugating Enzyme E2I spielt in den folgenden Prozessen eine Rolle:

cell cycle – cell division – chromosome segregation – interspecies interaction between organisms – mitosis – negative regulation of transcription, DNA-dependent – post-translational protein modification – regulation of protein metabolic process – ubiquitin-dependent protein catabolic process – modification-dependent protein catabolic process – multicellular organismal development – protein sumoylation – regulation of mitosis – negative regulation of transcription from RNA polymerase II promoter – positive regulation of steroid hormone receptor signaling pathway – positive regulation of transcription factor activity – proteasomal ubiquitin-dependent protein catabolic process – protein modification process – regulation of receptor activity

Ubiquitin-Conjugating Enzyme E2I ist wie folgt lokalisiert:

PML body – nucleus – synaptonemal complex – cytoplasm – dendrite – fibrillar center – nuclear body – synapse

Quelle: NCBI Entrez Gene, Gene Ontology