Die folgenden Gennamen und Gensymbole werden für Antigen Ubiquitin-Conjugating Enzyme E2B über verschiedene Spezies hinweg verwendet:

ubiquitin-conjugating enzyme E2B (RAD6 homolog) (UBE2B), Ubiquitin-conjugating enzyme E2 B (ube2b), ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae) (Ube2b), zgc:55512 (zgc:55512), ubiquitin-conjugating enzyme E2B (RAD6 homolog) (ube2b)

Zu den weiteren Synonymen zählen:

HR6B, UBC2, HHR6B, RAD6B, E2-17kDa, Rad6b, mHR6B, E2-14k, 2610301N02Rik, UBE2B, fc79h10, wu:fc79h10, zgc:100921, MGC78891, hr6b, ubc2, hhr6b, rad6b, MGC89687, e2-17kda, MGC133582

Auf Proteinebene tauchen folgende Bezeichner für Antigen Ubiquitin-Conjugating Enzyme E2B auf:

ubiquitin-conjugating enzyme E2B – E2 protein – ubiquitin-protein ligase B – ubiquitin carrier protein B – Ubiquitin-conjugating enzyme E2 B – ubiquitin-conjugating enzyme E2 B – E214K – RAD6 homolog B – OTTMUSP00000005786 – OTTMUSP00000005787 – ubiquitin conjugating enzyme – ubiquitin-conjugating enzyme E2B, RAD6 homolog – hypothetical protein LOC325470 – ubiquitin-conjugating enzyme E2B (RAD6 homolog) – novel protein similar to veretbrate ubiquitin-conjugating enzyme E2A (RAD6 homolog) (UBE2A) (zgc:55512) – HR6B – E2(14k) – ubiquitin conjugating-protein – ubiquitin-conjugating enzyme E2

Ubiquitin-Conjugating Enzyme E2B erfüllt eine Reihe von Funktionen:

ATP binding – ligase activity – nucleotide binding – protein binding – ubiquitin protein ligase binding – ubiquitin-protein ligase activity – small conjugating protein ligase activity – molecular_function

Ubiquitin-Conjugating Enzyme E2B spielt in den folgenden Prozessen eine Rolle:

Wnt receptor signaling pathway through beta-catenin – histone H2A ubiquitination – postreplication repair – protein autoubiquitination – protein monoubiquitination – protein polyubiquitination – protein stabilization – regulation of protein metabolic process – response to DNA damage stimulus – response to UV – response to drug – sperm axoneme assembly – spermatogenesis – ubiquitin-dependent protein catabolic process – DNA repair – chiasma assembly – histone lysine demethylation – in utero embryonic development – maintenance of chromatin silencing – negative regulation of apoptosis – negative regulation of histone phosphorylation – positive regulation of reciprocal meiotic recombination – post-translational protein modification – regulation of histone modification – synaptonemal complex organization – cellular response to insulin stimulus – chiasma formation – response to hypoxia – modification-dependent protein catabolic process

Ubiquitin-Conjugating Enzyme E2B ist wie folgt lokalisiert:

chromatin – cytoplasm – nucleus – plasma membrane – replication fork – XY body – membrane – nuclear chromatin – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology