Die folgenden Gennamen und Gensymbole werden für Antigen Ubiquitin-Activating Enzyme 3 über verschiedene Spezies hinweg verwendet:

ubiquitin-like modifier activating enzyme 3 (UBA3), ubiquitin-like modifier activating enzyme 3 (Uba3), ubiquitin-like modifier activating enzyme 3 (uba3), NEDD8-activating enzyme E1 catalytic subunit (ube1c), ubiquitin-activating enzyme 3 (LOC100343309)

Zu den weiteren Synonymen zählen:

UBE1C, hUBA3, MGC22384, DKFZp566J164, Ube1c, ube1c, zgc:55528, wu:fb75e04, wu:fc37b11, MGC140052, DKFZp459A0915, DKFZp459D1713, DKFZp459G1962, AI256736, AI848246, AW546539, A830034N06Rik

Auf Proteinebene tauchen folgende Bezeichner für Antigen Ubiquitin-Activating Enzyme 3 auf:

ubiquitin-activating enzyme 3 – Nedd8-activating enzyme hUba3 – UBA3, ubiquitin-activating enzyme E1 homolog – ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) – ubiquitin-activating enzyme E1C (homologous to yeast UBA3) – NEDD8-activating enzyme E1 catalytic subunit – NEDD8-activating enzyme E1C – ubiquitin-like modifier-activating enzyme 3 – ubiquitin-activating enzyme E1C – ubiquitin activating enzyme 3

Ubiquitin-Activating Enzyme 3 erfüllt eine Reihe von Funktionen:

ATP binding – acid-amino acid ligase activity – ligase activity – nucleotide binding – protein binding – protein heterodimerization activity – small protein activating enzyme activity – NEDD8 activating enzyme activity – binding – ligand-dependent nuclear receptor binding – transcription repressor activity – catalytic activity

Ubiquitin-Activating Enzyme 3 spielt in den folgenden Prozessen eine Rolle:

cell cycle – metabolic process – modification-dependent protein catabolic process – protein modification process – protein neddylation – proteolysis – endomitotic cell cycle – mitotic cell cycle – negative regulation of transcription – regulation of cell cycle

Ubiquitin-Activating Enzyme 3 ist wie folgt lokalisiert:

cellular_component – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology