Die folgenden Gennamen und Gensymbole werden für Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1B über verschiedene Spezies hinweg verwendet:

tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), TNF receptor-associated factor 2 (TRAF2), TNF receptor-associated factor 3 (TRAF3), TNF receptor-associated factor 6 (TRAF6), TNF receptor-associated factor 2 (Traf2), TNF receptor-associated factor 3 (Traf3), TNF receptor-associated factor 6 (Traf6), Tnf receptor-associated factor 2 (Traf2), TNF receptor-associated factor 2 (traf2), TRAF family member-associated NFKB activator (TANK), TNF receptor-associated factor 6 (LOC716907), TNF receptor-associated factor 3 (LOC100218184), TNF receptor-associated factor 3 (LOC100359083), tumor necrosis factor receptor superfamily, member 1B (LOC100222629)

Zu den weiteren Synonymen zählen:

p75, TBPII, TNFBR, TNFR2, CD120b, TNFR1B, TNFR80, TNF-R75, p75TNFR, TNF-R-II, TRAP, TRAP3, MGC:45012, LAP1, CAP-1, CRAF1, CD40bp, RNF85, MGC:3310, AI325259, amn, T-BAM, AI528849, AI851288, 2310003F17Rik, C630032O20Rik, MGC83471, TANK, TRAF2, LOC716907, LOC100218184, TNFRSF1B, MGC128726, TNFR-II

Auf Proteinebene tauchen folgende Bezeichner für Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1B auf:

tumor necrosis factor receptor 2 – p75 TNF receptor – soluble TNFR1B variant 1 – tumor necrosis factor beta receptor – tumor necrosis factor binding protein 2 – TNF receptor-associated factor 2 – tumor necrosis factor type 2 receptor associated protein 3 – TNF receptor-associated factor 3 – CD40 binding protein – LMP1 associated protein – CD40 associated protein 1 – CD40 receptor associated factor 1 – TNF receptor-associated factor 6 – OTTMUSP00000013078 – OTTMUSP00000013079 – E3 ubiquitin-protein ligase TRAF2 – TRAFAMN – OTTMUSP00000041798 – CD40 receptor-associated factor 1 – OTTMUSP00000015480 – E3 ubiquitin-protein ligase TRAF6 – TRAF family member-associated NFKB activator – TNF receptor-associated factor 2-like – tumor necrosis factor receptor superfamily, member 1B – tumor necrosis factor receptor-II – tumor necrosis factor receptor superfamily member 1B

Tumor Necrosis Factor Receptor Superfamily, Member 1B erfüllt eine Reihe von Funktionen:

protein binding – receptor activity – tumor necrosis factor receptor activity – metal ion binding – signal transducer activity – zinc ion binding – ubiquitin-protein ligase activity – mitogen-activated protein kinase kinase kinase binding – protein complex binding – ligase activity – sphingolipid binding

Tumor Necrosis Factor Receptor Superfamily, Member 1B spielt in den folgenden Prozessen eine Rolle:

apoptosis – activation of NF-kappaB-inducing kinase activity – activation of pro-apoptotic gene products – positive regulation of T cell activation – positive regulation of T cell cytokine production – positive regulation of interleukin-2 production – protein complex assembly – regulation of apoptosis – signal transduction – induction of apoptosis – T cell receptor signaling pathway – anti-apoptosis – induction of apoptosis by extracellular signals – membrane protein intracellular domain proteolysis – modification-dependent protein catabolic process – positive regulation of I-kappaB kinase/NF-kappaB cascade – protein polyubiquitination – negative regulation of glial cell apoptosis – positive regulation of NF-kappaB transcription factor activity – protein catabolic process – protein heterooligomerization – regulation of JNK cascade – regulation of immunoglobulin secretion – tumor necrosis factor-mediated signaling pathway – I-kappaB kinase/NF-kappaB cascade – JNK cascade – T-helper 1 type immune response – antigen processing and presentation of exogenous peptide antigen via MHC class II – bone remodeling – bone resorption – cell development – cytokine-mediated signaling pathway – immune response – interleukin-1-mediated signaling pathway – myeloid dendritic cell differentiation – neural tube closure – odontogenesis of dentine-containing tooth – organ morphogenesis – ossification – osteoclast differentiation – positive regulation of T cell proliferation – positive regulation of interleukin-12 biosynthetic process – positive regulation of interleukin-6 biosynthetic process – positive regulation of lipopolysaccharide-mediated signaling pathway – positive regulation of smooth muscle cell proliferation – positive regulation of transcription from RNA polymerase II promoter – protein autoubiquitination – positive regulation of JUN kinase activity – positive regulation of transcription factor activity – protein K63-linked ubiquitination – protein homotrimerization – RNA destabilization – cell death – cell surface receptor linked signal transduction – negative regulation of inflammatory response

Tumor Necrosis Factor Receptor Superfamily, Member 1B ist wie folgt lokalisiert:

extracellular region – integral to membrane – membrane raft – plasma membrane – cytoplasm – cytosol – cell cortex – protein complex – membrane fraction – nucleus – membrane

Quelle: NCBI Entrez Gene, Gene Ontology