Die folgenden Gennamen und Gensymbole werden für Antigen Transglutaminase 2, Tissue über verschiedene Spezies hinweg verwendet:

transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transglutaminase 2, C polypeptide (Tgm2), transglutaminase 2b (tgm2b), transglutaminase 2, C polypeptide (tgm2), transglutaminase 2 (TGM2), transglutaminase 2 (LOC100352148)

Zu den weiteren Synonymen zählen:

TG2, TGC, GNAH, G-ALPHA-h, TgaseII, TGM2, fc12b04, MGC136700, wu:fc12b04, zgc:136700, zgc:101081

Auf Proteinebene tauchen folgende Bezeichner für Antigen Transglutaminase 2, Tissue auf:

transglutaminase 2 – TGase C – TGase-H – C polypeptide – transglutaminase C – tissue transglutaminase – protein-glutamine-gamma-glutamyltransferase – transglutaminase 2, C polypeptide – tissue-type transglutaminase – transglutaminase 2b – transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

Transglutaminase 2, Tissue erfüllt eine Reihe von Funktionen:

GTP binding – acyltransferase activity – calcium ion binding – protein domain specific binding – protein-glutamine gamma-glutamyltransferase activity – transferase activity – enzyme binding

Transglutaminase 2, Tissue spielt in den folgenden Prozessen eine Rolle:

blood vessel remodeling – elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) – induction of apoptosis – isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine – peptide cross-linking – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of cell adhesion – positive regulation of inflammatory response – positive regulation of smooth muscle cell proliferation – protein homooligomerization – branching involved in salivary gland morphogenesis – salivary gland cavitation

Transglutaminase 2, Tissue ist wie folgt lokalisiert:

mitochondrion – plasma membrane – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology