Die folgenden Gennamen und Gensymbole werden für Antigen Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) über verschiedene Spezies hinweg verwendet:

transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcription factor 7-like 2, T-cell specific, HMG-box (Tcf7l2), transcription factor 7-like 2 (T-cell specific, HMG-box) (tcf7l2), transcription factor 7-like 2 (T-cell specific, HMG-box) (LOC100229459)

Zu den weiteren Synonymen zählen:

TCF4, TCF-4, Tcf4, TCF4B, TCF4E, Tcf-4, mTcf-4B, mTcf-4E, tcf4, TCF7L2, MGC128514, MGC155227

Auf Proteinebene tauchen folgende Bezeichner für Antigen Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) auf:

transcription factor 7-like 2 – mTCF-4 – T-cell factor 4 – OTTMUSP00000022195 – OTTMUSP00000022196 – OTTMUSP00000022198 – OTTMUSP00000022199 – OTTMUSP00000022200 – OTTMUSP00000022201 – OTTMUSP00000022202 – HMG box transcription factor 4 – T-cell-specific transcription factor 4 – transcription factor tcf4 – transcription factor 4 – transcriptional factor 4 – transcription factor 7-like 2 (T-cell specific, HMG-box)

Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) erfüllt eine Reihe von Funktionen:

RNA polymerase II transcription factor activity – beta-catenin binding – protein kinase binding – specific transcriptional repressor activity – transcription factor activity – transcription factor binding – DNA binding – protein binding – transcription regulator activity

Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) spielt in den folgenden Prozessen eine Rolle:

Wnt receptor signaling pathway through beta-catenin – anti-apoptosis – blood vessel development – cell cycle arrest – cell proliferation – fat cell differentiation – glucose homeostasis – myoblast cell fate commitment – pancreas development – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of heparan sulfate proteoglycan biosynthetic process – positive regulation of insulin secretion – regulation of hormone metabolic process – regulation of transcription – regulation of transcription from RNA polymerase II promoter – Wnt receptor signaling pathway – embryonic digestive tract morphogenesis – embryonic genitalia morphogenesis – embryonic hindgut morphogenesis – neural tube development – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – regulation of gene-specific transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – response to glucose stimulus – somatic stem cell maintenance – transcription

Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) ist wie folgt lokalisiert:

beta-catenin-TCF7L2 complex – nucleus – cytosol – transcription factor complex

Quelle: NCBI Entrez Gene, Gene Ontology