Die folgenden Gennamen und Gensymbole werden für Antigen Thrombin über verschiedene Spezies hinweg verwendet:

coagulation factor II (thrombin) receptor-like 2 (F2RL2), coagulation factor II (F2), coagulation factor II (thrombin) (F2), THROMBIN protein (THROMBIN)

Zu den weiteren Synonymen zählen:

PAR3, Cf2, FII, Cf-2, thrombin, F2, THROMBIN

Auf Proteinebene tauchen folgende Bezeichner für Antigen Thrombin auf:

coagulation factor II (thrombin) receptor-like 2 – thrombin receptor-like 2 – protease-activated receptor 3 – proteinase-activated receptor-3 – Coagulation factor II receptor-like 2 (protease-actovated receptor 3) – prothrombin – OTTMUSP00000015068 – coagulation factor II – thrombin – THROMBIN protein

Thrombin erfüllt eine Reihe von Funktionen:

G-protein coupled receptor activity – phosphoinositide phospholipase C activity – protein binding – receptor activity – thrombin receptor activity – calcium ion binding – catalytic activity – hydrolase activity – peptidase activity – serine-type endopeptidase activity – serine-type peptidase activity

Thrombin spielt in den folgenden Prozessen eine Rolle:

G-protein coupled receptor protein signaling pathway – blood coagulation – response to wounding – signal transduction – acute-phase response – metabolic process – platelet activation – positive regulation of cell growth – positive regulation of cell proliferation – positive regulation of phosphoinositide 3-kinase cascade – proteolysis – regulation of cell shape – thrombin receptor signaling pathway

Thrombin ist wie folgt lokalisiert:

apical plasma membrane – extracellular region – integral to plasma membrane – plasma membrane – extracellular space

Quelle: NCBI Entrez Gene, Gene Ontology