Die folgenden Gennamen und Gensymbole werden für Antigen Tafazzin über verschiedene Spezies hinweg verwendet:

tafazzin (TAZ), tafazzin (Taz), tafazzin (taz), tafazzin (AFUA_2G13960), tafazzin (AOR_1_318014), tafazzin (Tsp_06712), Tafazzin (taz), WW domain containing transcription regulator 1 (WWTR1), WW domain containing transcription regulator 1 (Wwtr1)

Zu den weiteren Synonymen zählen:

EFE, BTHS, EFE2, G4.5, Taz1, CMD3A, LVNCX, XAP-2, FLJ27390, AW107266, AW552613, 5031411C02Rik, 9130012G04Rik, MGC91803, zgc:91803, wu:fb39f12, MGC116399, MGC54019, TAZ, taz, GB11956, DKFZp586I1419, Taz, C78399, 2310058J06Rik, 2610021I22Rik

Auf Proteinebene tauchen folgende Bezeichner für Antigen Tafazzin auf:

tafazzin – OTTMUSP00000019253 – tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) – Tafazzin – WW domain containing transcription regulator 1 – transcriptional co-activator with PDZ-binding motif (TAZ) – WW domain-containing transcription regulator protein 1 – OTTMUSP00000037016 – transcriptional coactivator with PDZ binding motif – transcriptional coactivator with PDZ-binding motif

Tafazzin erfüllt eine Reihe von Funktionen:

1-acylglycerophosphocholine O-acyltransferase activity – acyltransferase activity – molecular_function – protein binding – protein homodimerization activity – transcription coactivator activity – transcription corepressor activity – transcription regulator activity – identical protein binding

Tafazzin spielt in den folgenden Prozessen eine Rolle:

cardiac muscle contraction – cardiac muscle tissue development – cardiolipin biosynthetic process – cristae formation – hemopoiesis – metabolic process – mitochondrial ATP synthesis coupled electron transport – mitochondrial respiratory chain complex I assembly – muscle contraction – skeletal muscle tissue development – phosphatidylglycerol metabolic process – heart development – heart looping – positive regulation of heart contraction – biological_process – hippo signaling cascade – negative regulation of canonical Wnt receptor signaling pathway – negative regulation of catenin protein nuclear translocation – negative regulation of protein amino acid phosphorylation – negative regulation of protein kinase activity – cilium morphogenesis – glomerulus development – negative regulation of fat cell differentiation – negative regulation of transcription from RNA polymerase II promoter – osteoblast differentiation – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – regulation of transcription – transcription

Tafazzin ist wie folgt lokalisiert:

cytoplasm – integral to membrane – membrane – mitochondrion – integral to mitochondrial outer membrane – cellular_component – nucleolus – nucleus – transcription factor complex

Quelle: NCBI Entrez Gene, Gene Ontology