Die folgenden Gennamen und Gensymbole werden für Antigen T-Box 5 über verschiedene Spezies hinweg verwendet:

T-box 5 (TBX5), T-box 5 (Tbx5), T-box 5 (tbx5), T-box 5 (LOC100356836)

Zu den weiteren Synonymen zählen:

HOS, TBX5, xtbx5

Auf Proteinebene tauchen folgende Bezeichner für Antigen T-Box 5 auf:

T-box 5 – T-box transcription factor TBX5 – T-box protein 5 – T-box transcription factor 5 – T-box transcription factor TBX5-like – t-box transcription factor TBX5-like

T-Box 5 erfüllt eine Reihe von Funktionen:

RNA polymerase II transcription factor activity – sequence-specific DNA binding – transcription factor activity – transcription factor binding – DNA binding – protein binding – sequence-specific DNA binding transcription factor activity – transcription activator activity – molecular_function

T-Box 5 spielt in den folgenden Prozessen eine Rolle:

cell-cell signaling – embryonic arm morphogenesis – embryonic limb morphogenesis – forelimb morphogenesis – heart development – induction of apoptosis – multicellular organismal development – negative regulation of cardiac muscle cell proliferation – negative regulation of cell migration – pericardium development – positive regulation of cardioblast differentiation – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of transcription, DNA-dependent – bundle of His development – embryonic forelimb morphogenesis – lung development – morphogenesis of an epithelium – pattern specification process – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription – regulation of transcription, DNA-dependent – transcription – biological_process – cardiac muscle cell differentiation – negative regulation of cell proliferation – cardiac left ventricle formation – response to retinoic acid – ventricular septum development

T-Box 5 ist wie folgt lokalisiert:

cytoplasm – nucleus – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology