Die folgenden Gennamen und Gensymbole werden für Antigen T-Box 3 über verschiedene Spezies hinweg verwendet:

T-box 3 (Tbx3), T-box 3 (TBX3), T-box 3 (tbx3)

Zu den weiteren Synonymen zählen:

D5Ertd189e, xtbx3, ums, xhl, tbx3-iso, TBX3, UMS, XHL, TBX3-ISO

Auf Proteinebene tauchen folgende Bezeichner für Antigen T-Box 3 auf:

T-box transcription factor TBX3 – T-box protein 3 – OTTMUSP00000038110 – T-box 3 (ulnar mammary syndrome) – T-box 3 – T-Box protein 3 – transcription factor Tbx3 – T-box 3 protein – T-box transcription factor TBX3-like – t-box transcription factor TBX3-like – bladder cancer related protein XHL

T-Box 3 erfüllt eine Reihe von Funktionen:

DNA binding – sequence-specific DNA binding transcription factor activity – transcription repressor activity – general transcriptional repressor activity – molecular_function – sequence-specific DNA binding – transcription factor activity – RNA polymerase II transcription factor activity

T-Box 3 spielt in den folgenden Prozessen eine Rolle:

blood vessel development – branching involved in mammary gland duct morphogenesis – cardiac muscle cell differentiation – cell aging – forelimb morphogenesis – heart looping – heart morphogenesis – in utero embryonic development – limb morphogenesis – limbic system development – mammary gland development – mammary placode formation – multicellular organismal development – negative regulation of apoptosis – negative regulation of transcription – negative regulation of transcription, DNA-dependent – organ morphogenesis – positive regulation of transcription, DNA-dependent – regulation of cell proliferation – regulation of transcription – regulation of transcription, DNA-dependent – specification of organ position – transcription – anterior/posterior axis specification, embryo – anti-apoptosis – biological_process – embryonic arm morphogenesis – embryonic digit morphogenesis – female genitalia development – follicle-stimulating hormone secretion – luteinizing hormone secretion – male genitalia development – mesoderm morphogenesis – negative regulation of myoblast differentiation – positive regulation of cell cycle – positive regulation of cell proliferation – skeletal system development – determination of anterior/posterior axis, embryo – regulation of transcription from RNA polymerase II promoter

T-Box 3 ist wie folgt lokalisiert:

nucleus – cellular_component – cytoplasm – nucleolus

Quelle: NCBI Entrez Gene, Gene Ontology