Die folgenden Gennamen und Gensymbole werden für Antigen Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 über verschiedene Spezies hinweg verwendet:

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (Slc11a1), solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (SLC11A1), solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (slc11a1)

Zu den weiteren Synonymen zählen:

Bcg, Itg, Lsh, Nramp1, MGC124692, LSH, NRAMP, NRAMP1, SLC11A1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 auf:

natural resistance-associated macrophage protein 1 – NRAMP 1 – natural resistance associated macrophage protein 1 – solute carrier family 11 (sodium/phosphate symporters), member 1 – solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 – natural resistance-associated macrophage protein 1-like

Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 erfüllt eine Reihe von Funktionen:

manganese ion transmembrane transporter activity – metal ion:hydrogen antiporter activity – molecular_function – protein homodimerization activity – transition metal ion transmembrane transporter activity – transporter activity – iron ion binding

Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 spielt in den folgenden Prozessen eine Rolle:

L-arginine import – MHC class II biosynthetic process – T cell cytokine production – T cell proliferation involved in immune response – activation of protein kinase activity – antigen processing and presentation of peptide antigen – biological_process – cadmium ion transmembrane transport – cellular cadmium ion homeostasis – cellular iron ion homeostasis – defense response to Gram-negative bacterium – defense response to bacterium – defense response to protozoan – divalent metal ion export – inflammatory response – interleukin-2 production – interleukin-3 production – ion transport – iron ion homeostasis – iron ion transport – mRNA stabilization – macrophage activation – manganese ion transmembrane transport – manganese ion transport – multicellular organismal iron ion homeostasis – negative regulation of cytokine production – nitrite transport – phagocytosis – positive regulation of T-helper 1 type immune response – positive regulation of cytokine production – positive regulation of dendritic cell antigen processing and presentation – positive regulation of gene expression – positive regulation of interferon-gamma production – positive regulation of phagocytosis – positive regulation of transcription from RNA polymerase II promoter – protein import into nucleus, translocation – respiratory burst – response to bacterium – response to interferon-gamma – response to lipopolysaccharide – vacuolar acidification – wound healing

Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 ist wie folgt lokalisiert:

cell outer membrane – cell surface – cellular_component – endosome membrane – integral to membrane – late endosome – lysosome – membrane – phagocytic vesicle membrane – plasma membrane – tertiary granule membrane – integral to plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology