Die folgenden Gennamen und Gensymbole werden für Antigen Silencer Factor B über verschiedene Spezies hinweg verwendet:

CCAAT/enhancer binding protein (C/EBP), beta (Cebpb)

Zu den weiteren Synonymen zählen:

LAP, TCF5, Il6dbp, NF-IL6

Auf Proteinebene tauchen folgende Bezeichner für Antigen Silencer Factor B auf:

CCAAT/enhancer binding protein beta – C/EBP beta – nuclear factor-IL6 – liver activating protein (LAP) – Liver activating protein (LAP also NF-IL6 nuclear factor-IL6 previously designated TCF5) – Liver activating protein (LAP, also NF-IL6, nuclear factor-IL6, previously designated TCF5)

Silencer Factor B erfüllt eine Reihe von Funktionen:

DNA binding – RNA polymerase II transcription factor activity, enhancer binding – protein binding – protein heterodimerization activity – protein homodimerization activity – sequence-specific DNA binding – transcription activator activity – transcription factor binding

Silencer Factor B spielt in den folgenden Prozessen eine Rolle:

anti-apoptosis – brown fat cell differentiation – embryonic placenta development – fat cell differentiation – induction of apoptosis – mammary gland epithelial cell differentiation – mammary gland epithelial cell proliferation – neuron differentiation – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – regulation of interleukin-6 biosynthetic process – regulation of transcription, DNA-dependent

Silencer Factor B ist wie folgt lokalisiert:

cytoplasm – nuclear matrix – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology