Die folgenden Gennamen und Gensymbole werden für Antigen Signal-Induced Proliferation-Associated 1 über verschiedene Spezies hinweg verwendet:

signal-induced proliferation-associated 1 (SIPA1), signal-induced proliferation associated gene 1 (Sipa1), signal-induced proliferation-associated 1 (Sipa1), Signal peptidase I (leader peptidase I) (sipA1)

Zu den weiteren Synonymen zählen:

SPA1, MGC17037, MGC102688, Spa1, KIAA4074, SIPA1, MGC148481

Auf Proteinebene tauchen folgende Bezeichner für Antigen Signal-Induced Proliferation-Associated 1 auf:

signal-induced proliferation-associated protein 1 – p130 SPA-1 – GTPase-activating protein Spa-1 – signal-induced proliferation-associated gene 1 – signal-induced proliferation associated gene 1 – signal-induced proliferation-associated 1 – Signal peptidase I (leader peptidase I) – signal-induced proliferation-associated protein 1-like

Signal-Induced Proliferation-Associated 1 erfüllt eine Reihe von Funktionen:

GTPase activator activity – Rap GTPase activator activity – protein binding – protein C-terminus binding

Signal-Induced Proliferation-Associated 1 spielt in den folgenden Prozessen eine Rolle:

cell proliferation – cytoskeleton organization – intracellular signaling cascade – negative regulation of cell adhesion – negative regulation of cell cycle – negative regulation of cell growth – regulation of small GTPase mediated signal transduction – regulation of cell cycle – cellular response to water deprivation

Signal-Induced Proliferation-Associated 1 ist wie folgt lokalisiert:

cytoplasm – extrinsic to membrane – intracellular – membrane – nucleus – perinuclear region of cytoplasm – protein complex – transport vesicle

Quelle: NCBI Entrez Gene, Gene Ontology