Die folgenden Gennamen und Gensymbole werden für Antigen Signal Transducer and Activator of Transcription 6 über verschiedene Spezies hinweg verwendet:

signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), signal transducer and activator of transcription 6 (Stat6), signal transducer and activator of transcription 6, interleukin-4 induced (stat6), signal transducer and activator of transcription 6 (STAT6)

Zu den weiteren Synonymen zählen:

STAT6B, STAT6C, D12S1644, IL-4-STAT, fj66g07, wu:fj66g07, STAT6, DKFZp459D186

Auf Proteinebene tauchen folgende Bezeichner für Antigen Signal Transducer and Activator of Transcription 6 auf:

signal transducer and activator of transcription 6 – STAT, interleukin4-induced – transcription factor IL-4 STAT – signal transducer and transcription activator 6 – signal transducer and activator of transcription 6, interleukin-4 induced – signal transducer and activator of transcription 6-like

Signal Transducer and Activator of Transcription 6 erfüllt eine Reihe von Funktionen:

calcium ion binding – protein binding – sequence-specific DNA binding – signal transducer activity – transcription factor activity – DNA binding – sequence-specific DNA binding transcription factor activity

Signal Transducer and Activator of Transcription 6 spielt in den folgenden Prozessen eine Rolle:

negative regulation of T-helper 2 type immune response – positive regulation of isotype switching to IgE isotypes – positive regulation of transcription from RNA polymerase II promoter – regulation of cell proliferation – signal transduction – cytokine-mediated signaling pathway – regulation of transcription – regulation of transcription, DNA-dependent – response to cytokine stimulus – transcription

Signal Transducer and Activator of Transcription 6 ist wie folgt lokalisiert:

cytoplasm – nucleolus – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology