Die folgenden Gennamen und Gensymbole werden für Antigen Signal Transducer and Activator of Transcription 5A über verschiedene Spezies hinweg verwendet:

signal transducer and activator of transcription 5A (STAT5A), signal transducer and activator of transcription 5A (Stat5a), signal transducer and activator of transcription 5B (Stat5b)

Zu den weiteren Synonymen zählen:

MGF, STAT5, AA959963, Stat5, STATA5, STAT5A/MGF, STAT5A

Auf Proteinebene tauchen folgende Bezeichner für Antigen Signal Transducer and Activator of Transcription 5A auf:

signal transducer and activator of transcription 5A – OTTMUSP00000002045 – OTTMUSP00000002046 – mammary gland factor STAT5A – mammary gland factor – signal transducer and activator of transcription 5 – signal transducer and activator of transcription 5B – Signal transducer and activator of transcription 5a – STAT5A, Mammary Gland Factor – signal transducer and activator of transcription 5A-like

Signal Transducer and Activator of Transcription 5A erfüllt eine Reihe von Funktionen:

calcium ion binding – phosphate binding – protein binding – signal transducer activity – transcription factor activity – DNA binding – double-stranded DNA binding – sequence-specific DNA binding – sequence-specific DNA binding transcription factor activity – glucocorticoid receptor binding

Signal Transducer and Activator of Transcription 5A spielt in den folgenden Prozessen eine Rolle:

2-oxoglutarate metabolic process – JAK-STAT cascade involved in growth hormone signaling pathway – Peyer's patch development – T cell differentiation in the thymus – T cell homeostasis – allantoin metabolic process – citrate metabolic process – creatine metabolic process – creatinine metabolic process – cytokine-mediated signaling pathway – development of secondary female sexual characteristics – development of secondary male sexual characteristics – fatty acid metabolic process – female pregnancy – isoleucine metabolic process – lactation – lipid storage – luteinization – natural killer cell differentiation – negative regulation of apoptosis – negative regulation of erythrocyte differentiation – oxaloacetate metabolic process – peptidyl-tyrosine phosphorylation – positive regulation of B cell differentiation – positive regulation of activated T cell proliferation – positive regulation of cell proliferation – positive regulation of gamma-delta T cell differentiation – positive regulation of inflammatory response – positive regulation of interleukin-2 biosynthetic process – positive regulation of mitotic cell cycle – positive regulation of multicellular organism growth – positive regulation of survival gene product expression – positive regulation of transcription from RNA polymerase II promoter – regulation of cell adhesion – regulation of epithelial cell differentiation – regulation of steroid metabolic process – response to peptide hormone stimulus – signal transduction – succinate metabolic process – taurine metabolic process – valine metabolic process – JAK-STAT cascade – epithelial cell differentiation involved in prostate gland development – mammary gland development – negative regulation of mast cell apoptosis – positive regulation of lymphocyte differentiation – positive regulation of mast cell differentiation – positive regulation of mast cell proliferation – positive regulation of natural killer cell differentiation – positive regulation of natural killer cell mediated cytotoxicity – prostate gland epithelium morphogenesis – regulation of transcription – regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – transcription – mammary gland involution – reproductive process in a multicellular organism – response to ethanol – response to nutrient levels – transcription from RNA polymerase II promoter – acute-phase response – cellular response to hormone stimulus – liver development – positive regulation of cellular component movement – positive regulation of natural killer cell proliferation – positive regulation of smooth muscle cell proliferation – progesterone metabolic process – regulation of multicellular organism growth – response to estradiol stimulus – response to hypoxia – response to interleukin-15 – response to interleukin-2 – response to interleukin-4 – response to lipopolysaccharide – sex differentiation

Signal Transducer and Activator of Transcription 5A ist wie folgt lokalisiert:

cytoplasm – nucleus – cytosol

Quelle: NCBI Entrez Gene, Gene Ontology