Die folgenden Gennamen und Gensymbole werden für Antigen Signal Transducer and Activator of Transcription 3 über verschiedene Spezies hinweg verwendet:

signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), signal transducer and activator of transcription 3 (Stat3), signal transducer and activator of transcription 3 (STAT3), signal transducer and activator of transcription 3 (stat3)

Zu den weiteren Synonymen zählen:

APRF, HIES, FLJ20882, MGC16063, Aprf, AW109958, 1110034C02Rik, MGC93551, MGC128731, STAT3, stat3

Auf Proteinebene tauchen folgende Bezeichner für Antigen Signal Transducer and Activator of Transcription 3 auf:

signal transducer and activator of transcription 3 – DNA-binding protein APRF – acute-phase response factor – OTTMUSP00000002052 – OTTMUSP00000002053 – OTTMUSP00000045315 – OTTMUSP00000045316 – acute phase response factor

Signal Transducer and Activator of Transcription 3 erfüllt eine Reihe von Funktionen:

calcium ion binding – hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity – protein dimerization activity – protein kinase binding – signal transducer activity – transcription activator activity – transcription factor activity – transcription factor binding – DNA binding – protein binding – sequence-specific DNA binding – sequence-specific DNA binding transcription factor activity

Signal Transducer and Activator of Transcription 3 spielt in den folgenden Prozessen eine Rolle:

JAK-STAT cascade involved in growth hormone signaling pathway – cell motion – cellular response to hormone stimulus – eating behavior – eye photoreceptor cell differentiation – glucose homeostasis – interleukin-6-mediated signaling pathway – interspecies interaction between organisms – negative regulation of transcription from RNA polymerase II promoter – nervous system development – response to estradiol stimulus – sexual reproduction – signal transduction – temperature homeostasis – JAK-STAT cascade – acute-phase response – cytokine-mediated signaling pathway – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – regulation of multicellular organism growth – regulation of transcription – regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – response to cytokine stimulus – transcription – transcription from RNA polymerase II promoter – response to drug – response to ethanol – response to organic cyclic substance – response to organic substance – response to peptide hormone stimulus

Signal Transducer and Activator of Transcription 3 ist wie folgt lokalisiert:

cytoplasm – nucleolus – nucleus – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology