Die folgenden Gennamen und Gensymbole werden für Antigen Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) über verschiedene Spezies hinweg verwendet:

signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), signal transduction and activation of transcription 3 (stat3), signal transducer and activator of transcription (STAT3), signal transducer and activator of transcription 3 (acute-phase response factor) (stat3)

Zu den weiteren Synonymen zählen:

APRF, HIES, FLJ20882, MGC16063, fc15d02, fl59g06, z-Stat3, MGC193054, wu:fc15d02, wu:fl59g06, STAT3, DKFZp469E1221

Auf Proteinebene tauchen folgende Bezeichner für Antigen Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) auf:

signal transducer and activator of transcription 3 – DNA-binding protein APRF – acute-phase response factor – signal transduction and activation of transcription 3 – signal transducer and activator of transcription 3 (acute-phase response factor) – signal transducer and activator of transcription – Signal transducer and activator of transcription 3 – signal transducer and activator of transcription 3-like

Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) erfüllt eine Reihe von Funktionen:

calcium ion binding – hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity – protein dimerization activity – protein kinase binding – signal transducer activity – transcription activator activity – transcription factor activity – transcription factor binding – protein binding

Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) spielt in den folgenden Prozessen eine Rolle:

JAK-STAT cascade involved in growth hormone signaling pathway – cell motion – cellular response to hormone stimulus – eating behavior – eye photoreceptor cell differentiation – glucose homeostasis – interleukin-6-mediated signaling pathway – interspecies interaction between organisms – negative regulation of transcription from RNA polymerase II promoter – nervous system development – response to estradiol stimulus – sexual reproduction – signal transduction – temperature homeostasis – cell migration involved in gastrulation – epithelial to mesenchymal transition – establishment of cell polarity – establishment of planar polarity – motor axon guidance – regulation of transcription, DNA-dependent

Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) ist wie folgt lokalisiert:

cytoplasm – nucleolus – nucleus – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology