Die folgenden Gennamen und Gensymbole werden für Antigen Signal Transducer and Activator of Transcription 1 über verschiedene Spezies hinweg verwendet:

signal transducer and activator of transcription 1, 91kDa (STAT1), signal transducer and activator of transcription 1, 91kDa (stat1), signal transducer and activator of transcription 1, 91kDa (RCJMB04_17i9), signal transducer and activator of transcription 1 (STAT1)

Zu den weiteren Synonymen zählen:

ISGF-3, STAT91, DKFZp686B04100, XStat1, STAT1, STAT4, isgf-3, stat91, MGC147452, DKFZp459D206

Auf Proteinebene tauchen folgende Bezeichner für Antigen Signal Transducer and Activator of Transcription 1 auf:

signal transducer and activator of transcription 1 – OTTHUMP00000205845 – transcription factor ISGF-3 components p91/p84 – signal transducer and activator of transcription-1 – signal transducer and activator of transcription 1, 91kDa – signal transducer and activator of transcription 4 – signal transducer and activator of transcription 1-alpha/beta – transcription factor ISGF-3 – signal transducer and activator of transcription 1-alpha/beta-like

Signal Transducer and Activator of Transcription 1 erfüllt eine Reihe von Funktionen:

calcium ion binding – hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity – protein binding – signal transducer activity – transcription factor activity

Signal Transducer and Activator of Transcription 1 spielt in den folgenden Prozessen eine Rolle:

I-kappaB kinase/NF-kappaB cascade – activation of caspase activity – interspecies interaction between organisms – regulation of transcription, DNA-dependent – response to virus – signal transduction – transcription from RNA polymerase II promoter – tyrosine phosphorylation of STAT protein – cytokine-mediated signaling pathway – lipopolysaccharide-mediated signaling pathway – response to exogenous dsRNA – response to lipopolysaccharide

Signal Transducer and Activator of Transcription 1 ist wie folgt lokalisiert:

cytoplasm – nucleolus – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology