Die folgenden Gennamen und Gensymbole werden für Antigen Serum Response Factor über verschiedene Spezies hinweg verwendet:

serum response factor (c-fos serum response element-binding transcription factor) (SRF), serum response factor (Srf), serum response factor (srf), blistered (bs), serum response factor (srf-A), serum response factor (c-fos serum response element-binding transcription factor) (Srf), serum response factor (Tsp_03174), serum response factor (c-fos serum response element-binding transcription factor) (LOC100230563), serum response factor (c-fos serum response element-binding transcription factor) (LOC100354695)

Zu den weiteren Synonymen zählen:

MCM1, AW049942, AW240594, srf1, MGC192699, BS, D-SRF, DSRF, DSrf/bs, DmSRF, Group IIc, SRF, Serf, ba, bs/DSRF, l(2)03267, pruned/DSRF, px, DmelCG3411, CG3411, srf-A, RGD1559787, Srf, bs, LOC100230563

Auf Proteinebene tauchen folgende Bezeichner für Antigen Serum Response Factor auf:

serum response factor (c-fos serum response element-binding transcription factor) – serum response factor – blistered, isoform A – CG3411-PA – bs-PA – drosophila serum response factor – balloon – blistered – pruned – blistered/Drosophila serum response factor – blistered, isoform B – CG3411-PB – bs-PB

Serum Response Factor erfüllt eine Reihe von Funktionen:

protein homodimerization activity – sequence-specific DNA binding – serum response element binding – specific RNA polymerase II transcription factor activity – transcription factor activity – transcription factor binding – DNA binding – protein binding – sequence-specific DNA binding transcription factor activity – RNA polymerase II transcription factor activity

Serum Response Factor spielt in den folgenden Prozessen eine Rolle:

angiogenesis involved in wound healing – cell migration involved in sprouting angiogenesis – heart development – heart looping – multicellular organismal development – muscle homeostasis – neuron development – positive regulation of cell differentiation – positive regulation of smooth muscle contraction – positive regulation of transcription from RNA polymerase II promoter – positive regulation of transcription initiation from RNA polymerase II promoter – positive regulation of transcription via serum response element binding – regulation of smooth muscle cell differentiation – regulation of transcription, DNA-dependent – response to cytokine stimulus – response to hormone stimulus – response to toxin – senescence – trophectodermal cell differentiation – actin filament organization – developmental growth – gastrulation – in utero embryonic development – long-term memory – mesoderm formation – muscle cell homeostasis – negative regulation of cell migration – negative regulation of cell proliferation – patterning of blood vessels – positive regulation of filopodium assembly – positive regulation of transcription – primitive streak formation – regulation of cell adhesion – regulation of transcription – transcription – apposition of dorsal and ventral imaginal disc-derived wing surfaces – cell fate commitment – imaginal disc-derived wing morphogenesis – open tracheal system development – terminal branching, open tracheal system – terminal cell fate specification, open tracheal system

Serum Response Factor ist wie folgt lokalisiert:

cytoplasm – nucleolus – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology