Die folgenden Gennamen und Gensymbole werden für Antigen Serotonin Transporter über verschiedene Spezies hinweg verwendet:

solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (Slc6a4), Serotonin transporter (SerT), serotonin transporter (SERT), solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (SLC6A4), serotonin transporter (Sert), serotonin transporter (5HTT)

Zu den weiteren Synonymen zählen:

SERT, dSERT, dSERT1, DmelCG4545, CG4545, SLC6A4, Sert, 5HTT

Auf Proteinebene tauchen folgende Bezeichner für Antigen Serotonin Transporter auf:

sodium-dependent serotonin transporter – 5HTT – 5HT transporter – serotonin transporter – solute carrier family 6, member 4 – Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter) – solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter) – CG4545-PA – SerT-PA – drosophila serotonin transporter – cocaine-sensitive serotonin transporter – plasma membrane transporter for serotonin reuptake – solute carrier family 6 member 4 – high-affinity serotonin transporter protein

Serotonin Transporter erfüllt eine Reihe von Funktionen:

Rab GTPase binding – actin filament binding – cocaine binding – monoamine transmembrane transporter activity – myosin binding – nitric-oxide synthase binding – protein binding – protein homodimerization activity – serotonin transmembrane transporter activity – serotonin:sodium symporter activity – symporter activity – cation channel activity – neurotransmitter:sodium symporter activity

Serotonin Transporter spielt in den folgenden Prozessen eine Rolle:

locomotory behavior – monoamine transport – neurotransmitter transport – positive regulation of cell cycle – positive regulation of gene expression – protein oligomerization – response to toxin – serotonin transport – serotonin uptake – thalamus development – phagocytosis, engulfment

Serotonin Transporter ist wie folgt lokalisiert:

cytosol – endomembrane system – endosome – endosome membrane – integral to plasma membrane – membrane fraction – membrane raft – plasma membrane – axon – nerve terminal

Quelle: NCBI Entrez Gene, Gene Ontology