Die folgenden Gennamen und Gensymbole werden für Antigen Selectin P über verschiedene Spezies hinweg verwendet:

selectin, platelet (Selp), selectin P (SELP), selectin P (Selp), selectin P (granule membrane protein 140kDa, antigen CD62) (SELP)

Zu den weiteren Synonymen zählen:

Grmp, CD62P, PADGEM, MGC129336, MGC129337, P-selectin, SELP, PSELECT, MGC124632

Auf Proteinebene tauchen folgende Bezeichner für Antigen Selectin P auf:

P-selectin – LECAM3 – GMP-140 – P selectin – granule membrane protein 140 – CD62 antigen-like family member P – leukocyte-endothelial cell adhesion molecule 3 – platelet activation dependent granule-external membrane protein – selectin P – PADGEM – selectin, platelet

Selectin P erfüllt eine Reihe von Funktionen:

binding – calcium-dependent protein binding – eukaryotic cell surface binding – glycoprotein binding – protein binding – sialic acid binding – sugar binding – fucose binding – heparin binding – lipopolysaccharide binding – oligosaccharide binding

Selectin P spielt in den folgenden Prozessen eine Rolle:

blood vessel morphogenesis – cell adhesion – cell-cell adhesion – cellular response to interleukin-6 – heterophilic cell-cell adhesion – inflammatory response – leukocyte cell-cell adhesion – leukocyte migration – leukocyte tethering or rolling – positive regulation of cell adhesion – positive regulation of leukocyte migration – positive regulation of platelet activation – regulation of cellular extravasation – response to lipopolysaccharide – response to organic cyclic substance

Selectin P ist wie folgt lokalisiert:

external side of plasma membrane – extracellular space – integral to membrane – membrane – membrane fraction – platelet alpha granule membrane – plasma membrane – platelet dense granule membrane

Quelle: NCBI Entrez Gene, Gene Ontology