Die folgenden Gennamen und Gensymbole werden für Antigen Secreted phosphoprotein 1 über verschiedene Spezies hinweg verwendet:

secreted phosphoprotein 1 (SPP1), secreted phosphoprotein 1 (Spp1), secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) (SPP1), zgc:111821 (zgc:111821)

Zu den weiteren Synonymen zählen:

OPN, BNSP, BSPI, ETA-1, MGC110940, OP, Bsp, Eta, Opn, Ric, Opnl, Apl-1, Spp-1, AA960535, AI790405, OSP, SPP1, spp1, MGC111821

Auf Proteinebene tauchen folgende Bezeichner für Antigen Secreted phosphoprotein 1 auf:

secreted phosphoprotein 1 – osteopontin – SPP1/CALPHA1 fusion – bone sialoprotein I – early T-lymphocyte activation 1 – secreted phosphoprotein-1 (osteopontin, bone sialoprotein) – osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein – secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) – 2AR – minopontin – OTTMUSP00000029095 – OTTMUSP00000029097 – OTTMUSP00000029098 – OTTMUSP00000029099 – OTTMUSP00000029100 – bone sialoprotein 1 – osteopontin-like protein – 44 kDa bone phosphoprotein – early T-lymphocyte activation 1 protein – calcium oxalate crystal growth inhibitor protein – SPP-1 – Sialoprotein (osteopontin) – spp1 protein – Osteopontin – secreted phosphoprotein-1

Secreted phosphoprotein 1 erfüllt eine Reihe von Funktionen:

cytokine activity – protein binding – extracellular matrix binding – molecular_function

Secreted phosphoprotein 1 spielt in den folgenden Prozessen eine Rolle:

biomineral formation – cell adhesion – decidualization – embryo implantation – ossification – response to vitamin D – anti-apoptosis – biomineral tissue development – osteoblast differentiation – positive regulation of bone resorption – positive regulation of cell-substrate adhesion – response to organic substance – response to steroid hormone stimulus – cell differentiation – inflammatory response – negative regulation of collateral sprouting of intact axon in response to injury – biological_process

Secreted phosphoprotein 1 ist wie folgt lokalisiert:

extracellular region – extracellular space – apical part of cell – cell projection – cytoplasm – membrane-bounded vesicle – perinuclear region of cytoplasm – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology