Die folgenden Gennamen und Gensymbole werden für Antigen Secreted Frizzled-Related Protein 1 über verschiedene Spezies hinweg verwendet:

secreted frizzled-related protein 1 (SFRP1), secreted frizzled-related protein 1 (Sfrp1), secreted frizzled-related protein 1 (sfrp1), Secreted frizzled-related protein 1 (sfrp1), secreted frizzled-related protein 1 (LOC100231868)

Zu den weiteren Synonymen zählen:

FRP, FRP1, FrzA, FRP-1, SARP2, sFRP-1, AW011917, AW107218, AW742929, 2210415K03Rik, SFRP1, CSFRP1, frp, frp1, frzA, frp-1, sarp2, sfrp1, LOC100231868

Auf Proteinebene tauchen folgende Bezeichner für Antigen Secreted Frizzled-Related Protein 1 auf:

secreted frizzled-related protein 1 – secreted apoptosis-related protein 2 – OTTMUSP00000023228 – secreted frizzled-related sequence protein 1 – sFRP-1 – secreted frizzled related protein 1 – Secreted frizzled-related protein 1

Secreted Frizzled-Related Protein 1 erfüllt eine Reihe von Funktionen:

protein binding – Wnt-protein binding – frizzled binding – identical protein binding – molecular_function

Secreted Frizzled-Related Protein 1 spielt in den folgenden Prozessen eine Rolle:

Wnt receptor signaling pathway – anatomical structure morphogenesis – anti-apoptosis – cell differentiation – multicellular organismal development – prostate gland development – signal transduction – somitogenesis – Wnt receptor signaling pathway, planar cell polarity pathway – actin cytoskeleton organization – anterior/posterior pattern formation – bone trabecula formation – convergent extension involved in somitogenesis – development of primary male sexual characteristics – digestive tract morphogenesis – female gonad development – hemopoiesis – male gonad development – negative regulation of BMP signaling pathway – negative regulation of JUN kinase activity – negative regulation of Wnt receptor signaling pathway – negative regulation of apoptosis – negative regulation of canonical Wnt receptor signaling pathway – negative regulation of gene expression – negative regulation of ossification – negative regulation of osteoblast differentiation – negative regulation of osteoblast proliferation – negative regulation of osteoclast differentiation – neural crest cell fate commitment – neural tube closure – neural tube development – positive regulation of apoptosis – positive regulation of fat cell differentiation – prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis – regulation of branching involved in prostate gland morphogenesis – regulation of establishment of planar polarity – regulation of ossification – somatic stem cell maintenance – substrate adhesion-dependent cell spreading – ureteric bud development – canonical Wnt receptor signaling pathway – cellular response to prostaglandin E stimulus – negative regulation of cell proliferation – negative regulation of fibroblast proliferation

Secreted Frizzled-Related Protein 1 ist wie folgt lokalisiert:

extracellular region – extracellular space – plasma membrane – cellular_component – extracellular matrix

Quelle: NCBI Entrez Gene, Gene Ontology