Die folgenden Gennamen und Gensymbole werden für Antigen SMAD Family Member 5 über verschiedene Spezies hinweg verwendet:

MAD homolog 5 (Drosophila) (smad5), SMAD family member 5 (smad5), SMAD family member 5 (SMAD5), Mothers against decapentaplegic homolog 5 (smad5)

Zu den weiteren Synonymen zählen:

SBN, mad, smd5, madh5, fb67b04, sb:cb400, wu:fb67b04, jv5-1, smad10, SMAD5, MGC139219, MADH5, DKFZp468M0619, smad5

Auf Proteinebene tauchen folgende Bezeichner für Antigen SMAD Family Member 5 auf:

SMAD family member 5 – pgy – piggytail – somitabun – SMA- and MAD-related protein 5 – MAD (mothers against decapentaplegic, Drosophila) homolog 5 – mothers against decapentaplegic homolog 5 – Mothers against decapentaplegic homolog 5 – mothers against decapentaplegic homolog 5-like

SMAD Family Member 5 erfüllt eine Reihe von Funktionen:

protein binding – transcription factor activity

SMAD Family Member 5 spielt in den folgenden Prozessen eine Rolle:

BMP signaling pathway – blood vessel morphogenesis – determination of dorsal/ventral asymmetry – determination of left/right symmetry – determination of ventral identity – dorsal convergence – dorsal/ventral pattern formation – embryonic heart tube development – embryonic pattern specification – multicellular organismal development – otic placode formation – regulation of transcription – regulation of transcription, DNA-dependent – transcription – transforming growth factor beta receptor signaling pathway – cardiac muscle contraction – erythrocyte differentiation – germ cell development – osteoblast fate commitment – positive regulation of osteoblast differentiation – positive regulation of transcription from RNA polymerase II promoter

SMAD Family Member 5 ist wie folgt lokalisiert:

cytoplasm – intracellular – nucleus – transcription factor complex

Quelle: NCBI Entrez Gene, Gene Ontology