Die folgenden Gennamen und Gensymbole werden für Antigen SMAD, Mothers Against DPP Homolog 5 über verschiedene Spezies hinweg verwendet:

SMAD family member 5 (SMAD5), SMAD family member 5 (Smad5)

Zu den weiteren Synonymen zählen:

Dwfc, JV5-1, MADH5, DKFZp781C1895, DKFZp781O1323, Madh5

Auf Proteinebene tauchen folgende Bezeichner für Antigen SMAD, Mothers Against DPP Homolog 5 auf:

SMAD family member 5 – MAD homolog 5 – SMA- and MAD-related protein 5 – SMAD, mothers against DPP homolog 5 – mothers against decapentaplegic homolog 5 – MAD, mothers against decapentaplegic homolog 5 – mothers against decapentaplegic, drosophila, homolog of, 5 – SMAD 5 – mothers against DPP homolog 5

SMAD, Mothers Against DPP Homolog 5 erfüllt eine Reihe von Funktionen:

protein binding – receptor signaling protein activity – transcription activator activity – transcription factor activity – transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity – sequence-specific DNA binding transcription factor activity – ubiquitin protein ligase binding

SMAD, Mothers Against DPP Homolog 5 spielt in den folgenden Prozessen eine Rolle:

BMP signaling pathway – embryonic pattern specification – regulation of transcription, DNA-dependent – signal transduction – transforming growth factor beta receptor signaling pathway – Mullerian duct regression – cardiac muscle contraction – cellular response to organic cyclic substance – erythrocyte differentiation – germ cell development – ossification – osteoblast fate commitment – positive regulation of osteoblast differentiation – positive regulation of transcription from RNA polymerase II promoter – protein amino acid phosphorylation – regulation of ossification – ureteric bud development

SMAD, Mothers Against DPP Homolog 5 ist wie folgt lokalisiert:

cytoplasm – cytosol – integral to membrane – intracellular – nucleoplasm – nucleus – transcription factor complex

Quelle: NCBI Entrez Gene, Gene Ontology