Die folgenden Gennamen und Gensymbole werden für Antigen S-Phase Kinase-Associated Protein 1 über verschiedene Spezies hinweg verwendet:

S-phase kinase-associated protein 1 (SKP1), S-phase kinase-associated protein 1 (SK18), S-phase kinase-associated protein 1 (SK4), S-phase kinase-associated protein 1 (skp1), S-phase kinase-associated protein 1 (LOC100340043), S-phase kinase-associated protein 1A (Skp1a), S-phase kinase-associated protein 1 (Skp1), S-phase kinase-associated protein 1A (p19A) (skp1a), SKP1 (S PHASE KINASE-ASSOCIATED PROTEIN 1); protein binding / ubiquitin-protein ligase (SKP1)

Zu den weiteren Synonymen zählen:

OCP2, p19A, EMC19, SKP1A, OCP-II, TCEB1L, MGC34403, ASK18, F14N23.11, F14N23_11, SK18, SKP1-like 18, ASK4, SK4, SKP1-like 4, T20H2.8, T20H2_8, SKP1, 15kDa, Tceb1l, p19Skp1, 2610043E24Rik, 2610206H23Rik, Skp1a, skp1a, MGC64317, MGC73186, zgc:73186, ocp2, emc19, ocp-ii, tceb1l, MGC127638, ARABIDOPSIS SKP1 HOMOLOGUE 1, ASK1, ATSKP1, S PHASE KINASE-ASSOCIATED PROTEIN 1, T4O12.17, T4O12_17, UFO INTERACTING PROTEIN 1, UIP1, ocp-2, DKFZp459G0415

Auf Proteinebene tauchen folgende Bezeichner für Antigen S-Phase Kinase-Associated Protein 1 auf:

S-phase kinase-associated protein 1 – organ of Corti protein 2 – cyclin A/CDK2-associated p19 – RNA polymerase II elongation factor-like protein OCP2 – transcription elongation factor B (SIII), polypeptide 1-like – SCF complex component – S-phase kinase-associated protein 1A – OTTMUSP00000005802 – OTTMUSP00000005803 – cyclin A/CDK2-associated protein p19 – cyclin-A/CDK2-associated protein p19 – transcription elongation factor B (SIII), polypeptide 1 (15 kDa),-like – p19A – p19skp1 – S-phase kinase-associated protein 1A (p19A) – SKP1 (S PHASE KINASE-ASSOCIATED PROTEIN 1); protein binding / ubiquitin-protein ligase – OCP-II protein

S-Phase Kinase-Associated Protein 1 erfüllt eine Reihe von Funktionen:

protein binding – ubiquitin-protein ligase activity – kinase activity

S-Phase Kinase-Associated Protein 1 spielt in den folgenden Prozessen eine Rolle:

positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle – ubiquitin-dependent protein catabolic process – protein ubiquitination – SCF-dependent proteasomal ubiquitin-dependent protein catabolic process – positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle – male meiosis – mitosis – negative regulation of DNA recombination – response to cadmium ion

S-Phase Kinase-Associated Protein 1 ist wie folgt lokalisiert:

SCF ubiquitin ligase complex – cytosol – nucleoplasm – cytoplasm – nucleolus – nucleus – phragmoplast – plasma membrane – spindle – ubiquitin ligase complex

Quelle: NCBI Entrez Gene, Gene Ontology